Tau protein and its role in bloodbrain barrier dysfunction

A Michalicova, P Majerova, A Kovac - Frontiers in molecular …, 2020 - frontiersin.org
The bloodbrain barrier (BBB) plays a crucial role in maintaining the … BBB dysfunction is
growing. The opening of the BBB and subsequent infiltration of serum components to the brain

Sepsis-associated encephalopathy and blood-brain barrier dysfunction

Q Gao, MS Hernandes - Inflammation, 2021 - Springer
… Major mediators of SAE-induced endothelial barrier dysfunction that have been discussed
… , endothelial barrier dysfunction, sphingolipid metabolism, and mitochondrial dysfunction, all …

Bloodbrain barrier dysfunction, seizures and epilepsy

EA Van Vliet, E Aronica, JA Gorter - Seminars in cell & Developmental …, 2015 - Elsevier
… Schematic representation of processes involved in bloodbrain barrier dysfunction and
epilepsy. The entry of leukocytes from the blood into the brain via the adhesion molecules ICAM-…

Oxidative stress and bloodbrain barrier dysfunction under particular consideration of matrix metalloproteinases

C Lehner, R Gehwolf, H Tempfer, I Krizbai… - Antioxidants & redox …, 2011 - liebertpub.com
… metalloproteinases leading to bloodbrain barrier dysfunctionJ Neurochem1015665762007…
and matrix metalloproteinases leading to bloodbrain barrier dysfunction. J Neurochem 101…

Blood-brain barrier dysfunction in normal aging and neurodegeneration: mechanisms, impact, and treatments

AV Andjelkovic, M Situ, AF Citalan-Madrid… - Stroke, 2023 - Am Heart Assoc
Cerebral endothelial cells and their linking tight junctions form a unique, dynamic and multi-functional
interface, the blood-brain barrier (BBB). The endothelium is regulated by …

Bloodbrain barrier dysfunction, TGFβ signaling, and astrocyte dysfunction in epilepsy

UWE Heinemann, D Kaufer, A Friedman - Glia, 2012 - Wiley Online Library
Dysfunction of the bloodbrain barrier (BBB) is a hallmark of brain insults and is usually …
linking vascular pathology, and specifically BBB dysfunction, to seizures and epilepsy. We …

Blood-brain barrier dysfunction in CNS disorders and putative therapeutic targets: an overview

SR Archie, A Al Shoyaib, L Cucullo - Pharmaceutics, 2021 - mdpi.com
The blood-brain barrier (BBB) is a fundamental component of the central nervous system (CNS).
Its functional and structural integrity is vital to maintain the homeostasis of the brain

Bloodbrain barrier dysfunction: the undervalued frontier of hypertension

V Katsi, M Marketou, S Maragkoudakis… - Journal of Human …, 2020 - nature.com
The bloodbrain barrier (BBB) constitutes the complex anatomic and physiologic interface
between the intravascular compartment and the central nervous system, and its integrity is …

Neutrophils and the bloodbrain barrier dysfunction after trauma

M Scholz, J Cinatl, M Schädel‐Höpfner… - Medicinal Research …, 2007 - Wiley Online Library
… where cariporide prevented stress-induced epithelial barrier dysfunction.Overall, these
findings indicate that the pathophysiology underlying BBB dysfunction has to be targeted at the …

COVID-19 and cognitive impairment: neuroinvasive and bloodbrain barrier dysfunction

Y Chen, W Yang, F Chen, L Cui - Journal of Neuroinflammation, 2022 - Springer
… may spread to other brain regions via infected nerve … bloodbrain barrier (BBB), composed
of neurovascular units (NVUs) lining the brain microvasculature, acts as a physical barrier