The blood-brain barrier (BBB) cellular constituents and their molecular interactions critically
regulate immune activation within the central nervous system (CNS) such that it is protected …

… Although considered primarily to be an ischemic process, the vessel and tissue damage
could also be explained by dysfunctional endothelium or blood–brain barrier (BBB) leak, not …

… Accumulating evidence points to vascular pathology and dysfunction of the blood-brain
barrier (BBB) as a potential link between severe TBI and neurodegeneration. Moreover, …

The blood-brain barrier (BBB), which protects the CNS from pathogens, is composed of
specialized brain microvascular endothelial cells (BMECs) joined by tight junctions and …

… barrier in a microfluidic platform and verified that it successfully mimics certain aspects of
bEC barrier dysfunction, notably the increase in permeability observed in human AD patients. …

… The blood-brain barrier (BBB) consists of specialized cells … blood to brain parenchyma,
protecting the brain’s microenvironment. If one of the BBB components starts to fail, its dysfunction …

… Here, we provide evidence that the blood–brain barrier (BBB) is disrupted in regions of … in
the brain of a patient with PSP. This report represents the first description of BBB dysfunction in …

… Blood vessels in the CNS form a specialized and critical structure, the blood–brain barrier
(… that regulate BBB function in health and dysfunction during disease. Using endothelial cell …

The characteristics and mechanisms enabling the blood-brain barrier (BBB) to maintain the
milieu of the brain have been reviewed in detail elsewhere (Banks and Kastin, 1987; …

… cascade that leads to breakdown of the blood brain barrier (BBB) and neurodegeneration. …
the blood and the brain, thereby regulating the microenvironment within the brain parenchyma…