Blood-brain barrier dysfunction amplifies the development of neuroinflammation: understanding of cellular events in brain microvascular endothelial cells for …

F Takata, S Nakagawa, J Matsumoto… - Frontiers in cellular …, 2021 - frontiersin.org
… intercellular communication between brain endothelial cells and brain perivascular cells (…
cellular components, such as signaling molecules in brain endothelial cells, and non-cellular

'Sealing off the CNS': cellular and molecular regulation of bloodbrain barriergenesis

JA Siegenthaler, F Sohet, R Daneman - Current opinion in neurobiology, 2013 - Elsevier
events as blood vessels enter neural tissue. The induction of these properties appears to
be orchestrated by a series of different cellular interactions occurring sequentially during brain

[PDF][PDF] Structural pathways for macromolecular and cellular transport across the blood-brain barrier during inflammatory conditions. Review

AS Lossinsky, RR Shivers - Histology and histopathology, 2004 - digitum.um.es
Review Structural pathways for macromolecular and cellular transport across the blood-brain
barrier during inflammatory conditio Page 1 Summary. This review presents an overview of …

[HTML][HTML] The blood-brain barrier in brain homeostasis and neurological diseases

N Weiss, F Miller, S Cazaubon, PO Couraud - Biochimica et Biophysica …, 2009 - Elsevier
… In conclusion, the complex cellular and molecular changes leading to BBB breakdown after
an ischemia/reperfusion event remain to be further understood, before novel treatments of …

The cell biology of the blood-brain barrier

LL Rubin, JM Staddon - Annual review of neuroscience, 1999 - annualreviews.org
… keep toxic substances out of the brain, they are poorlyinformed about its underlying biology,
and until recently, few studies applieddetailed cellular and molecular biology to this problem…

Cellular response of the blood-brain barrier to injury: potential biomarkers and therapeutic targets for brain regeneration

MM Tenreiro, R Ferreira, L Bernardino, MA Brito - Neurobiology of Disease, 2016 - Elsevier
… These cells and cellular structures have been documented in numerous diseases, and … a
cascade of events that can result in BBB disruption. These events include endothelial swelling, …

Molecular and cellular permeability control at the bloodbrain barrier

SM Gloor, M Wachtel, MF Bolliger, H Ishihara… - Brain research …, 2001 - Elsevier
… These properties allow cerebral microcapillaries to develop a tight cellular layer with a … It is
worthwhile considering that many pathogens use proteolysis to cross cellular boundaries. For …

The bloodbrain barrier

R Daneman, A Prat - Cold Spring Harbor perspectives in …, 2015 - cshperspectives.cshlp.org
… Astrocytes provide a cellular link between the neuronal circuitry and blood vessels. This …
Furthermore, it remains unclear what the cellular signaling events that coordinate these …

[HTML][HTML] Blood-brain barrier: from physiology to disease and back

MD Sweeney, Z Zhao, A Montagne… - Physiological …, 2018 - journals.physiology.org
… The blood-brain barrier (BBB) prevents neurotoxic plasma components, blood cells, and
pathogens from entering the brain. At the … In this review, we first examine molecular and cellular

The bloodbrain barrier: an overview: structure, regulation, and clinical implications

P Ballabh, A Braun, M Nedergaard - Neurobiology of disease, 2004 - Elsevier
… compounds from blood to brain. Three cellular elements of the brain microvasculature compose
… These events are mediated through heterotrimeric G protein and protein kinase C (PKC) …