… Loss of blood–brain barrier integrity during neurological disease in humans and rodent
models. (A, B) Imaging the brain of a human patient following stroke. (A) T2 fluid attenuated …

… treatment of brain tumours, inflammation and Alzheimer’s disease. In … healthy BBB and
promote fluctuations in BBB permeability in disease states will be key to elucidate disease …

… Blood–brain … diseases such as Alzheimer’s disease. This review will discuss current
knowledge and key unanswered questions regarding the blood–brain barrier in health and disease. …

This article introduces the special issue on “Blood–Brain Barrier and Epilepsy.” We review
briefly current understanding of the structure and function of the blood–brain barrier (BBB), …

The blood-brain barrier (BBB) is the regulated interface between the peripheral circulation
and the central nervous system (CNS). Although originally observed by Paul Ehrlich in 1885, …

… brain. BBB breakdown, due to disruption of the tight junctions, altered transport of molecules
… blood and brain and brain and blood, aberrant angiogenesis, vessel regression, brain …

The blood–brain barrier ( BBB ) is a complex vascular structure consisting of microvascular
endothelial cells that line the vessel wall, astrocyte end‐feet, pericytes, as well as the basal …

The blood–brain barrier (BBB) is a critical regulator of CNS homeostasis. It possesses physical
and biochemical characteristics (ie tight junction protein complexes, transporters) that are …

Blood vessels in the CNS form a specialized and critical structure, the blood–brain barrier (BBB).
We present a resource to understand the molecular mechanisms that regulate BBB …

… possessed by the brain endothelial cells (ECs) that form the walls of the blood vessels. These
… the brain functions in both health and disease contexts. blood vessels convey blood from …