Pathogenesis and treatment strategies of COVID-19-related hypercoagulant and thrombotic complications

MA Haimei - Clinical and Applied Thrombosis/Hemostasis, 2020 - journals.sagepub.com
coagulation system of COVID-19 patients generally show enhanced coagulation and
thrombosis. Complications of severe and critical COVID-19 include ARDS, embolism or pulmonary …

Blood clots in COVID-19 patients: Simplifying the curious mystery

S Biswas, V Thakur, P Kaur, A Khan, S Kulshrestha… - Medical …, 2021 - Elsevier
… -2 pathogenesis are coming out every day, and one such mystery is the formation of mysterious
blood clots in the various tissues and organs of COVID-19 … endothelium of blood vessels …

COVID-19 pathogenesis and clinical manifestations

RAH Acosta, ZE Garrigos, JR Marcelin… - Infectious Disease …, 2022 - id.theclinics.com
COVID-19 affects many organs and has a variety of clinical presentations. In this review, we
cover various clinical manifestations of COVID-19 … equally in the pathogenesis of COVID-19, …

Endothelial dysfunction and immunothrombosis as key pathogenic mechanisms in COVID-19

A Bonaventura, A Vecchié, L Dagna… - Nature Reviews …, 2021 - nature.com
… As the coagulation cascade is dysregulated in COVID-19, anticoagulation approaches
have been explored for the treatment, particularly of patients with incident venous …

The pathogenesis of COVID-19: Hypercoagulation and D-dimer in thrombotic complications

L Dubey, H Lytvyn, O Dorosh… - Journal of Health …, 2023 - digitalscholarship.unlv.edu
… In COVID-19, the inflammation and blood coagulation systems are … A high level of DD
in blood plasma is consistently … coagulation plays a key role in COVID-19 pathogenesis [3]. …

Cytokine storm associated coagulation complications in COVID-19 patients: Pathogenesis and Management

SR Savla, KS Prabhavalkar, LK Bhatt - … of anti-infective therapy, 2021 - Taylor & Francis
pathogenesis of SARS-CoV-2 infection, generation of cytokine storm, the interdependence
between inflammation and coagulation… hemostatic system formed a blood clot resulting in the …

The pro-inflammatory cytokines in COVID-19 pathogenesis: What goes wrong?

D Darif, I Hammi, A Kihel, IEI Saik, F Guessous… - … pathogenesis, 2021 - Elsevier
… production shows the dual role of platelets in worsening both inflammation and coagulation.
… that degrades blood clots [83]. IL-6, a cytokine that is significantly elevated in severe …

The emerging role of neutrophils in the pathogenesis of thrombosis in COVID-19

V Iliadi, I Konstantinidou, K Aftzoglou, S Iliadis… - International journal of …, 2021 - mdpi.com
pathogenesis of endothelitis. Overall, this review summarizes recent progress in research on
the pathogenesis of COVID-19, … synergistic roles of immune and coagulation systems in the …

What we know (and do not know) regarding the pathogenesis of pulmonary thrombosis in COVID-19

G Lippi, EJ Favaloro - Seminars in Thrombosis and Hemostasis, 2023 - thieme-connect.com
… on the pathogenesis of SARS-CoV-2 infection converge now to unmask intriguing scenarios
in the pathogenesis of pulmonary thrombosis, where development of blood clots may also …

Blood clots and TAM receptor signalling in COVID-19 pathogenesis

G Lemke, GJ Silverman - Nature reviews immunology, 2020 - nature.com
… the exuberant blood clotting and immune hyper-reaction seen in patients with COVID-19
may … This agent is protein S, which is both an anticoagulant in the blood coagulation cascade …