The effects of heterologous immunization with prime-boost COVID-19 vaccination against SARS-CoV-2

TC Ho, YMA Chen, HP Chan, CC Chang, KP Chuang… - Vaccines, 2021 - mdpi.com
Coronavirus Disease 2019 (COVID-19) pandemic, which is caused by the severe acute
respiratory syndrome coronavirus 2 (SARS-CoV… global herd immunity against SARS-CoV-2. The …

Protective mucosal immunity against SARS-CoV-2 after heterologous systemic prime-mucosal boost immunization

D Lapuente, J Fuchs, J Willar, A Vieira Antão… - Nature …, 2021 - nature.com
… Concomitantly, the intranasal boost strategies lead to complete protection against a
SARS-CoV-2 infection in mice. Our data thus suggest that mucosal booster immunizations after …

mRNA booster immunization elicits potent neutralizing serum activity against the SARS-CoV-2 Omicron variant

H Gruell, K Vanshylla, P Tober-Lau, D Hillus… - Nature medicine, 2022 - nature.com
… However, mRNA booster immunizations in vaccinated and … This study demonstrates that
booster immunizations can … immune response to SARS-CoV-2, and booster immunizations (that …

Heterologous immunization with inactivated vaccine followed by mRNA-booster elicits strong immunity against SARS-CoV-2 Omicron variant

F Zuo, H Abolhassani, L Du, A Piralla… - Nature …, 2022 - nature.com
… Here we observed that an mRNA vaccine booster in … of homologous mRNA-vaccine or a
boost of mRNA vaccine after infection, … Our study demonstrates that mRNA vaccine booster in …

Impaired humoral and cellular immunity after SARS-CoV-2 BNT162b2 (tozinameran) prime-boost vaccination in kidney transplant recipients

A Sattler, E Schrezenmeier, UA Weber… - The Journal of …, 2021 - Am Soc Clin Investig
booster immunization after 21 days. Blood samples for cellular analysis were collected on
day 8 ± 1 after boost… day 0 and day 8 ± 1 after boost. Sera of 24 KTx patients were additionally …

A homologous or variant booster vaccine after Ad26. COV2. S immunization enhances SARS-CoV-2–specific immune responses in rhesus macaques

X He, M Aid, A Chandrashekar, J Yu… - Science Translational …, 2022 - science.org
… of protection against SARS-CoV-2 in humans remain to be determined, we speculate that
the substantially enhanced immune responses after boost immunization will lead to improved …

Protection against SARS-CoV-2 transmission by a parenteral prime—Intranasal boost vaccine strategy

D Christensen, C Polacek, DJ Sheward, L Hanke… - …, 2022 - thelancet.com
… -prime mucosal boost is an effective strategy for protecting against SARS-CoV-2 infection and
… prime - mucosal boost was superior to parenteral only immunization for protecting against …

Is booster dose strategy sufficient for omicron variant of SARS-CoV-2?

VP Chavda, V Apostolopoulos - Vaccines, 2022 - mdpi.com
… The objective of a booster dose is to restore vaccine effectiveness from the immune … A
booster immunization offers re-exposure to the immunizing antigen after initial immunization. It is …

mRNA vaccination boosts cross-variant neutralizing antibodies elicited by SARS-CoV-2 infection

L Stamatatos, J Czartoski, YH Wan, LJ Homad, V Rubin… - Science, 2021 - science.org
… , but a single immunization boosted neutralizing titers against all variants and SARS-CoV-1
by up … targeting the receptor binding domain and was not boosted by a second immunization. …

Heterologous prime-boost immunizations with chimpanzee adenoviral vectors elicit potent and protective immunity against SARS-CoV-2 infection

J Liu, K Xu, M Xing, Y Zhuo, J Guo, M Du, Q Wang… - Cell Discovery, 2021 - nature.com
SARS-CoV-2 infection in mouse lungs. Strikingly, we found that heterologous prime-boost
immunization … antibodies produced against the highly transmissible SARS-CoV-2 variants B.…