Defects in the adherens junction complex (E-cadherin/β-catenin) in inflammatory bowel disease

S Mehta, A Nijhuis, T Kumagai, J Lindsay… - Cell and tissue …, 2015 - Springer
The epithelial monolayer of the intestine is a selective barrier permitting nutrient and
electrolyte absorption yet acting to protect the underlying tissue compartments and cellular …

Wnt–β-catenin activation epigenetically reprograms Treg cells in inflammatory bowel disease and dysplastic progression

J Quandt, S Arnovitz, L Haghi, J Woehlk, A Mohsin… - Nature …, 2021 - nature.com
… with inflammatory bowel disease during inflammation and early dysplasia. Activating Wnt–β-catenin
signaling in human and murine T reg cells was sufficient to recapitulate the disease-…

Immunohistochemical expression of CDX2, β-catenin, and TP53 in inflammatory bowel disease-associated colorectal cancer

…, JF Flejou, MP Chenard, B Duclos… - … bowel diseases, 2011 - academic.oup.com
Background Inflammatory bowel disease (IBD) exposes patients to an increased risk of
colorectal cancer (i-CRC) and differences between i-CRC and sporadic colorectal cancer (s-CRC…

Over-expression of neurotensin high-affinity receptor 1 (NTS1) in relation with its ligand neurotensin (NT) and nuclear ß-catenin in inflammatory bowel disease-related …

C Bossard, F Souazé, A Jarry, S Bezieau, JF Mosnier… - Peptides, 2007 - Elsevier
… As it was previously described that NTS1 gene activation could occur by neurotensin itself
or by tcf/β-catenin pathway, we performed NT and β-catenin immunohistochemistry to gain …

[HTML][HTML] WNT-pathway components as predictive markers useful for diagnosis, prevention and therapy in inflammatory bowel disease and sporadic colorectal cancer

A Serafino, N Moroni, M Zonfrillo, F Andreola… - Oncotarget, 2014 - ncbi.nlm.nih.gov
… /β-catenin signaling not only dominates the early stages of sporadic colorectal cancer (SCC),
but could also represent the connection between inflammatory bowel diseases (… β-catenin

The expression of Wnt/beta-catenin signaling molecule in inflammatory bowel diseases treated with bone marrow mesenchymal stem cell transplantation

Y Xing, X Xie, Z Yuan, Y Cui, Y Li, Y Nie… - Chinese Journal of Tissue …, 2015 - cjter.com
… was used for establishing inflammatory bowel diseases rat models. Bone marrow … β-catenin
signaling molecule was detected in the large intestine tissue of inflammatory bowel disease

Resveratrol attenuates inflammatory bowel disease in mice by regulating SUMO1

J Wang, Z Zhang, A Fang, K Wu, X Chen… - Biological and …, 2020 - jstage.jst.go.jp
… To investigate the role of resveratrol in DSS-induced colitis, we first established a stable
model of inflammatory bowel disease induced by 3% DSS. We then split this group into two and …

βCatenin Regulation in Sporadic Colorectal Carcinogenesis: Not as Simple as APC

E Fredericks, G Dealtry, S Roux - Canadian Journal of …, 2018 - Wiley Online Library
… Using qPCR and IHC, we compared β-catenin, PPARγ, COX-2, and IL-… bowel disease (IBD),
and irritable bowel syndrome (IBS), against a normal control population. Results. β-catenin

Expression of catenins and E‐cadherin during epithelial restitution in inflammatory bowel disease

AJ Karayiannakis, KN Syrigos… - The Journal of …, 1998 - Wiley Online Library
… on Crohn’s disease. These findings indicate that altered expression of E-cadherin, -catenin,
and p120 occurs during mucosal ulceration in inflammatory bowel disease. These changes …

The role of CDX2 in inflammatory bowel disease.

M Coskun - Danish medical journal, 2014 - europepmc.org
… High levels of pro-inflammatory cytokines are present in the gut of patients with inflammatory
bowel disease (IBD) and have a crucial role in the dysfunction of mucosal homeostasis. …