… In addition, specific AMPs are reported to be associated with inflammatory bowel disease
(IBD) … to weaken defense mechanism against enteric microbiota by lowering the antimicrobial …

… Impaired antimicrobial peptide expression has also been implicated in inflammatory bowel
disease, underscoring the essential role of antimicrobial defenses in maintaining intestinal …

… in its defense against … of antimicrobial peptides produced by the intestines, the defensins.
We concentrate on their emerging role in the pathogenesis of inflammatory bowel disease, …

… hepaticus and a reduced antimicrobial activity of crypt secretions … , antimicrobial peptide
expression and intestinal defense in … host-defense as a primary factor in disease pathogenesis. …

… as Crohn's disease and ulcerative colitis are incompletely understood. Recently, antimicrobial
… Antimicrobial peptides are pivotal for intestinal defense, shaping the composition of the …

… in microbiota-mediated development of inflammatory bowel disease, obesity, and obesity-…
microbiota composition that leads to inflammatory bowel disease and steatohepatitis (50, 106). …

… ′s disease (CD) – a form of inflammatory bowel disease (… small intestinal CD and Paneth
cell antimicrobial function. Thus, … paramount importance of antimicrobial host defense in small …

… The pathogenesis of inflammatory bowel disease (IBD) … antimicrobial barrier morphologically
consists of a single layer of epithelial cells and the mucus and constitutes the first defense …

… to antimicrobial defenses. Enterocytes can produce enzymes, such as intestinal alkaline
phosphatase and acyloxyacyl hydrolase, that modify LPS to reduce its inflammatory effects.6, 11 …

… are associated with increased risk for inflammatory bowel disease. Although the exact
mechanisms remain poorly understood, the increased risk of disease could be due in part to …