… The influence of genetics in the etiology of inflammatory bowel disease (IBD) was initially …
with genetic syndromes. These early observations paved the way to molecular genetics in IBD, …

… ’s disease (CD) are related polygenic diseases that share … than 50 confirmed inflammatory
bowel disease genes/loci, a … is associated with inflammatory bowel disease susceptibility, …

… bowel diseases (IBD) comprise complex genetic disorders, with multiple contributing genes.
… containing IBD susceptibility genes, with some observed uniquely in Crohn’s disease (CD) …

… We suggest that inflammatory bowel disease represents a number of distinct conditions of …
predisposing genetic and environmental factors may be shared between subtypes of disease. …

… genetic predisposition to inflammatory bowel diseases has grown progressively since the
familial occurrence of inflammatory bowel disease … relevant susceptibility genes might provide …

… studies (GWAS) in inflammatory bowel disease (IBD). In … alleles for coding and noncoding
genetic variation. In the small … most human genes is regulated by noncoding genetic variations…

… Here, recent progress made in understanding the genetic basis of inflammatory bowel
disease is reviewed, with particular reference to work carried out in Oxford. These studies have …

… The primary goal of genetic studies in IBD is the identification and prioritization of mechanisms
contributing to expression of clinical disease… The plethora of murine genetic models of IBD …

… when our understanding of genetic underpinnings of inflammatory bowel disease (IBD) has
… Determining the clinical relevance of how these susceptible genes shape the development …

… the IBD susceptibility genes for which the … genes, discovered by genome-wide association
studies). In addition, we will summarize the controversies regarding other putative IBD genes …