… of inflammatory bowel disease (IBD) has been established by twin, targeted-sequencing,
and genome-wide association studies. These studies identified many risk loci, and research is …

… association datasets from the two diseases 25. This underlines the … of genetic variants in 74
IBD risk loci on the susceptibility to … -specific risk loci for the acute and chronic subphenotype. …

… of IBD risk loci: a meta-analysis of all GWAS and Immunochip data from a total of 75 000
individuals increased the number of risk loci to 163 37. Most of these genetic risk loci contribute …

… -HLA PSC risk loci, we used a Bayesian test of colocalization 27 to identify loci with strong
… Four of the 18 PSC risk loci have not been associated at genome-wide significance with IBD …

… risk proteome in human serum. In particular, we screened protein products encoded at IBD
risk loci … and to further differentiate between different disease subtypes. We thus propose a list …

… Identifying shared and disease-specific susceptibility loci for Crohn's disease (CD) and …
between the inflammatory bowel diseases. More than 30 CD susceptibility loci have been …

… obtained from patients with Crohn’s disease or ulcerative colitis and from healthy controls. …
IBD risk loci. A subset of patients and controls were genotyped for IBD-associated risk SNPs. …

… Bowel Diseases (IBD) are polygenic chronic inflammatory disorders, and hundreds of IBD-associated
genetic loci … to these loci, however, has been limited to a handful of loci and mostly …

… Whether Crohn's disease (CD) and ulcerative colitis (UC) represent … bowel disease (IBD).
Recently, genome-wide association studies (GWAS) have identified several susceptibility loci, …

… Besides the previously known risk locus NOD2, this study identified CD-risk variants in the
interleukin 23 receptor (IL23R) gene. This was further replicated in cohorts of both CD and UC …