Inflammatory bowel disease susceptibility loci defined by genome scan meta-analysis of 1952 affected relative pairs

DA van Heel, SA Fisher, A Kirby, MJ Daly… - Human molecular …, 2004 - academic.oup.com
diseases) have a strong genetic component. Although over 20 putative susceptibility loci
have been identified by individual genome scans, the majority of these loci have not been …

Characteristics of Japanese inflammatory bowel disease susceptibility loci

Y Arimura, H Isshiki, K Onodera, K Nagaishi… - Journal of …, 2014 - Springer
susceptibility to UC but reduce CD risk. Moreover, we found individual disease risk loci: …
that of common susceptibility loci to IBD was modest (odds ratio ranged from 1.13 to 1.24). …

Susceptibility loci in inflammatory bowel disease

M Parkes, J Satsangi, GM Lathrop, JI Bell, DP Jewell - The Lancet, 1996 - thelancet.com
… SIR—Techniques of genome searching for complex disease susceptibility loci have … of
inflammatory bowel disease demonstrated strong evidence for linkage of both Crohn’s disease (…

Two stage genome–wide search in inflammatory bowel disease provides evidence for susceptibility loci on chromosomes 3, 7 and 12

J Satsangi, M Parkes, E Louis, L Hashimoto, N Kato… - Nature …, 1996 - nature.com
… of susceptibility genes in complex polygenic disorders""9. We undertook a two-stage genome
search for susceptibility genes in inflammatory bowel disease … of susceptibility loci for both …

[PDF][PDF] Genomewide search in Canadian families with inflammatory bowel disease reveals two novel susceptibility loci

JD Rioux, MS Silverberg, MJ Daly, AH Steinhart… - The American Journal of …, 2000 - cell.com
susceptibility to IBD that are segregating at different frequencies in the given populations.
Considering (a) that not all IBD-susceptibility loci … genomewide search for susceptibility loci in a …

Identification of novel susceptibility loci for inflammatory bowel disease on chromosomes 1p, 3q, and 4q: Evidence for epistasis between 1p and IBD1

JH Cho, DL Nicolae, LH Gold… - Proceedings of the …, 1998 - National Acad Sciences
… , one-third Ashkenazim, in the four above inflammatory bowel disease candidate loci, we
found significant evidence for only the IBD1 locus (SRB and JHC, unpublished observations). …

A genome-wide search identifies potential new susceptibility loci for Crohn's disease

Y Ma, JD Ohmen, Z Li, GL Bentley… - … bowel diseases, 1999 - academic.oup.com
… From four genome-wide scans, putative susceptibility loci on chromosome 16 (IBD1 … loci
on chromosomes 12 and 16. The aim of this study is to identify other potential susceptibility loci

Mapping susceptibility loci in inflammatory bowel disease: why and how?

M Parkes, J Satsangi, D Jewell - Molecular Medicine Today, 1997 - cell.com
… The cause of the inflammatory bowel diseases Crohn's disease … genetic loci probably contribute
to disease susceptibility, … of a number of putative susceptibility loci. With large-scale, fine-…

Investigation of multiple susceptibility loci for inflammatory bowel disease in an Italian cohort of patients

A Latiano, O Palmieri, T Latiano, G Corritore, F Bossa… - PloS one, 2011 - journals.plos.org
Background Recent GWAs and meta-analyses have outlined about 100 susceptibility genes/loci
for inflammatory bowel diseases (IBD). In this study we aimed to investigate the …

Susceptibility locus for inflammatory bowel disease on chromosome 16 has a role in Crohn's disease, but not in ulcerative colitis

JD Ohmen, HY Yang, KK Yamamoto… - Human Molecular …, 1996 - academic.oup.com
… Most importantly with respect to this locus, our data also seem to indicate that there is … and
UC groups with respect to this locus. The susceptibility locus appears to be involved only in …