… fit brain ageing models may provide brain age estimates that are most discriminant of
individuals … This is not unexpected as tightly-fitting brain age models naturally produce brain-age …

… in 35 countries to study brain imaging data worldwide, discovering factors that modulate
brain structure, integrity, connectivity, and patterns of brain differences in major brain diseases. …

… brain differ functionally and structurally. Despite over a century of research, the extent to which
brain asymmetry is influenced by sex, handedness, age, … of subcortical brain asymmetries, …

… Ageing and its associated health conditions present a major challenge to individuals and
societies worldwide. To address this challenge, increasing efforts are being made towards the …

… be reconsidered, and individuals appreciate that brain, mental, … to find out urgently why and
apply the lessons worldwide. … , socioeconomic, and individual factors and customized to the …

… , a spike of cases has been noted worldwide in a range of non-… overarching brain age
estimation concept which, through brain … trajectories in normal brains at an individual level [2]. A …

… controls worldwide show reliable but subtle effects of brain aging … and unseen cohorts of
individuals with depression collected … to the growing area of brain age research by attempting to …

… of the same individual might act as a marker of hemisphere-specific brain health imbalance,
… individuals born in different decades, which influences individual predispositions for brain …

… (i) violates the conceptual foundation of brain-age modelling; and (ii) is highly … brain-age
modelling aims at learning the ‘normal’ trajectory of ageing by selecting a group of individuals …

… Every year, the World Federation of Neurology (WFN) celebrates World Brain Day on July
22… is “Brain health in an ageing population”. Worldwide, more than 800 million individuals are …