Blood–brain barrier dysfunction in brain diseases: Clinical experience

K Schoknecht, H Shalev - Epilepsia, 2012 - Wiley Online Library
… –brain barrier dysfunction are diverse and may range from physical endothelial damage in
traumatic brainClinically, blood–brain barrier dysfunction is often detected using contrast-…

The role of the blood brain barrier in neurodegenerative disorders and their treatment

AM Palmer - Journal of Alzheimer's Disease, 2011 - content.iospress.com
… This review will consider brain disorders and the progress and prospects made in
discovering medicines to treat them, with particular emphasis on the role of the BBB in both …

Imaging blood–brain barrier dysfunction as a biomarker for epileptogenesis

G Bar-Klein, S Lublinsky, L Kamintsky, I Noyman… - Brain, 2017 - academic.oup.com
… confirm blood–brain barrier dysfunction and neuroinflammation. … Our results show that early
blood–brain barrier pathology in the … of blood–brain barrier pathology as a clinically relevant …

Blood–brain barrier breakdown is an early biomarker of human cognitive dysfunction

DA Nation, MD Sweeney, A Montagne, AP Sagare… - Nature medicine, 2019 - nature.com
… In individuals with mild cognitive impairment, increased CSF sPDGFRβ correlates with …
(MRI) measures of blood–brain barrier (BBB) dysfunction 8 . Consistent with findings that a …

Overview and introduction: the blood–brain barrier in health and disease

NJ Abbott, A Friedman - Epilepsia, 2012 - Wiley Online Library
… –Brain Barrier and Epilepsy.’’ We review briefly current understanding of the structure and
function of the blood–brain barrier (… of cerebral blood vessels is one of three main barrier sites …

[HTML][HTML] Blood-brain barrier leakage in Alzheimer's disease: From discovery to clinical relevance

G Nehra, B Bauer, AMS Hartz - Pharmacology & therapeutics, 2022 - Elsevier
… their susceptibility to barrier leakage based … barrier dysfunction in clinical and postmortem
studies, summarize changes that lead to barrier leakage in patients and highlight the clinical

Blood–brain barrier dysfunction: the undervalued frontier of hypertension

V Katsi, M Marketou, S Maragkoudakis… - Journal of Human …, 2020 - nature.com
… To obtain the best experience, we recommend you use a more up to date browser (or turn
off compatibility mode in Internet Explorer). In the meantime, to ensure continued support, we …

Neurotoxicology of the brain barrier system: new implications

W Zheng - Journal of Toxicology: Clinical Toxicology, 2001 - Taylor & Francis
… The implication of brain barriers in certain … -induced barrier dysfunction in the etiology of
any of these disorders … about brain barrier systems in central nervous system disorders by …

Blood-brain barrier disruption in neuro-oncology: strategies, failures, and challenges to overcome

BS Karmur, J Philteos, A Abbasian, BE Zacharia… - Frontiers in …, 2020 - frontiersin.org
… Gadolinium, administered immediately after sonication was complete, was used to
confirm precise disruption of the blood-brain barrier as indicated by the nine small areas of …

The blood-brain barrier dysfunction in sepsis

T Barichello, JS Generoso, A Collodel, F Petronilho… - … barriers, 2021 - Taylor & Francis
… -brain barrier (BBB) breaks down, allowing and facilitating the entry of peripheral immune cells
into the brain, … , which is associated with BBB dysfunction; provide evidence of biomarkers …