[HTML][HTML] Quantifying blood-brain barrier leakage in small vessel disease: review and consensus recommendations

MJ Thrippleton, WH Backes, S Sourbron… - Alzheimer's & …, 2019 - Elsevier
Cerebral small vessel disease (cSVD) comprises pathological processes of the small vessels
in the brain that … that endothelial dysfunction, including blood-brain barrier (BBB) failure, is …

Blood–brain barrier leakage is more widespread in patients with cerebral small vessel disease

CE Zhang, SM Wong, HJ van de Haar, J Staals… - Neurology, 2017 - AAN Enterprises
brain barrier (BBB) dysfunction may occur in normal aging but may also play a pivotal role in
the pathophysiology of cerebral small vessel disease … extent of BBB leakage in patients with …

Blood–brain barrier leakage increases with small vessel disease in acute ischemic stroke

F Arba, R Leigh, D Inzitari, SJ Warach, M Luby… - Neurology, 2017 - AAN Enterprises
… In patients with acute ischemic stroke, we aimed to investigate the relation between
preexisting small vessel disease (SVD) and the amount of blood–brain barrier (BBB) leakage in …

Blood-brain barrier impairment and hypoperfusion are linked in cerebral small vessel disease

SM Wong, JFA Jansen, CE Zhang, EI Hoff, J Staals… - Neurology, 2019 - AAN Enterprises
… Blood-brain barrier leakage is more widespread in patients with cerebral small vessel disease
Blood-brain barrier leakage in patients with early Alzheimer disease. Radiology 2016;281:…

Blood-brain barrier and cerebral small vessel disease

JM Wardlaw - Journal of the neurological sciences, 2010 - Elsevier
… We found that the lacunar patients had more leaky blood-brain barrier in the white matter
than cortical stroke patients (p < 0.0001) and also in CSF (p = 0.003), with no difference …

[HTML][HTML] Blood-brain barrier failure as a core mechanism in cerebral small vessel disease and dementia: evidence from a cohort study

JM Wardlaw, SJ Makin, MCV Hernández… - Alzheimer's & …, 2017 - Elsevier
… was pathogenic of diffuse brain damage in cerebral small vessel disease. … Small vessel
disease (SVD) is a common contributor to dementia. Subtle blood-brain barrier (BBB) leakage

[HTML][HTML] Blood-brain barrier dysfunction in small vessel disease related intracerebral hemorrhage

WM Freeze, HIL Jacobs, FHBM Schreuder… - Frontiers in …, 2018 - frontiersin.org
… -brain barrier dysfunction in the etiology of spontaneous intracerebral hemorrhage due to
cerebral small vessel disease… that investigated perihematomal BBB leakage or plasma markers …

Blood-brain barrier dysfunction and cerebral small vessel disease (arteriolosclerosis) in brains of older people

LR Bridges, J Andoh, AJ Lawrence… - … of Neuropathology & …, 2014 - academic.oup.com
… blood-brain barrier protects brain tissue from potentially harmful plasma components. Small
vessel disease (… that are impermeable to large plasma proteins but permit leakage of a small …

Blood-brain barrier leakage in patients with early Alzheimer disease

HJ Van De Haar, S Burgmans, JFA Jansen… - Radiology, 2016 - pubs.rsna.org
leakage in the WM hyperintensity), diabetes status, and other noncerebral vascular disease
We also used linear regression to investigate the association between BBB leakage and …

[HTML][HTML] Blood–brain barrier leakage in relation to white matter hyperintensity volume and cognition in small vessel disease and normal aging

CE Zhang, SM Wong, R Uiterwijk, WH Backes… - Brain imaging and …, 2019 - Springer
… Blood–brain barrier (BBB) leakage increases with age and is involved in the … of cerebral
small vessel disease (cSVD). We examined the relationship between BBB leakage and white …