… The neurovascular unit comprises endothelial cells, pericytes and astrocytes that together confer unique properties on the blood–brainbarrier. The endothelial cells that line the …
K Nakamura, T Ikeuchi, K Nara, CS Rhodes… - Journal of Cell …, 2019 - rupress.org
… pericyte behaviors by examining integrin expression in cultured brainpericytes, as well as in brain … Both brainpericytes and brain endothelial cells strongly expressed ITGA5 (integrin α5…
… Heterogeneity of the neurovascular unit (NVU): current research has revealed high heterogeneity of eg, astrocytes and pericytes within the CNS and among different brain areas. The …
M Segarra, MR Aburto, A Acker-Palmer - Trends in neurosciences, 2021 - cell.com
… The ECs are surrounded by mural cells (pericytes or smooth muscle cells) that are … The tightness of the BBB and the crosstalk between its cellular components are highly dynamic and …
… CD13 is an alanyl aminopeptidase, which is a cell surface marker in the brainpericyte vasculature identified in resting pericytes [19, 20]. CD13 plays a role in tumor invasion, …
J Chen, Y Luo, H Hui, T Cai, H Huang… - Proceedings of the …, 2017 - National Acad Sciences
… as a dynamic coordinator regulating the communication between ECs and pericytes within … acts as an essential regulator to coordinate pericyte–EC communication and BBB formation …
… human anatomical complexity of brainbarriers, contributing to … -derived endothelial cells, brainpericytes, and astrocytes as self-… validated microvessel-pericyte/astrocyte dynamic contact-…
E Vandenhaute, L Dehouck, MC Boucau… - Current …, 2011 - ingentaconnect.com
… brainbarrier (BBB) is a dynamic cellular complex that is responsible for the maintenance of brain … can be used to reproduce most of the barrier's in vivo features (low paracellular …
MA Mäe, L He, S Nordling… - Circulation …, 2021 - Am Heart Assoc
… To define nearest neighbor relationships between cells, we next applied trajectory space (tSpace) analysis, which recapitulates dynamic and spatial relationships better than uniform …