Glioma Cell Interactions with Fetal Rat Brain Aggregates in Vitro and with Brain Tissue in Vivo

R Bjerkvig, OD Laerum, O Mella - Cancer research, 1986 - AACR
glioma cells into isogeneic solid brain tissue in organ culture (9). Here the glioma cells invaded
and replaced the brain tissue… complete destruction of the normal tissue. Although such an …

The brain tissue response to surgical injury and its possible contribution to glioma recurrence

L Hamard, D Ratel, L Selek, F Berger… - Journal of neuro …, 2016 - Springer
… Because some residual glioma cells always remain in the tumor resection … the brain tissue
response to SBI can also participate to glioma recurrence at the resection margin. Brain tissue

[PDF][PDF] Glioma cell migration dynamics in brain tissue assessed by multimodal optical imaging

CJ Liu, GA Shamsan, T Akkin, DJ Odde - Biophysical journal, 2019 - cell.com
… Despite the ability of U251 glioma cells to navigate diverse brain … of glioblastoma invasion
into the brain. Compared with white matter tracts, vasculature is more correlated with glioma

Microregional extracellular matrix heterogeneity in brain modulates glioma cell invasion

AC Bellail, SB Hunter, DJ Brat, C Tan… - … of biochemistry & cell …, 2004 - Elsevier
… The invasion of neoplastic cells into healthy brain tissue is a pathologic hallmark of gliomas
and … Transformed glial cells share the common attributes of the invasion process, including …

Stimulation of extracellular matrix components in the normal brain by invading glioma cells

JCA Knott, R Mahesparan… - … journal of cancer, 1998 - Wiley Online Library
… In conclusion, we have shown that normal brain tissue has the ability to produce … confronted
with invading glioma cells. Our results show that the glioma cells express specific integrins …

Reduced connexin43 expression in high‐grade human brain glioma cells

RP Huang, MZ Hossain, A Sehgal… - Journal of surgical …, 1999 - Wiley Online Library
gliomas. Results: High levels of cx43 were observed in all normal brain tissue and in glioma
… weak in grade III gliomas and almost undetectable in grade IV gliomas. Conclusions: Our …

Isolation and characterization of human malignant glioma cells from histologically normal brain

DL Silbergeld, MR Chicoine - Journal of neurosurgery, 1997 - thejns.org
… In summary, tumor cells were cultured from histologically normal brain acquired from a …
glioma cells (and hence the inadequacy of frozen-section evaluation of resection margins). Cell

Glioblastoma cells release factors that disrupt blood-brain barrier features

SW Schneider, T Ludwig, L Tatenhorst, S Braune… - Acta …, 2004 - Springer
cells, it is conceivable that malignant astrocytes have lost this ability due to dedifferentiation.
Alternatively, glioma cells … , eventually leading to BBB disruption within invaded brain tissue. …

Transplanted glioma cells migrate and proliferate on host brain vasculature: a dynamic analysis

A Farin, SO Suzuki, M Weiker, JE Goldman, JN Bruce… - Glia, 2006 - Wiley Online Library
… analysis of glioma cell infiltration in living brain tissue and reveals that the migration and
proliferation of transplanted glioma cells is directed by interactions with host brain vasculature. …

Interactions of glioma cells and extracellular matrix

W Paulus, JC Tonn - Journal of neuro-oncology, 1995 - Springer
… dermally derived brain tumors has been less well in… gliomas critically depend on the
interaction of glioma cells with the ECM, such as the diffuse invasion of brain tissue by glioma cells