Glioma cells release excitotoxic concentrations of glutamate

ZC Ye, H Sontheimer - Cancer research, 1999 - AACR
… Moreover, if our reasoning holds true, that glutamate release from tumors into the peritumoral
brain tissue may contribute to seizures, then phenylglycine compounds may reduce the …

Matrix metalloproteinases and tissue inhibitors of metalloproteinases in human gliomas

A Nakano, E Tani, K Miyazaki, Y Yamamoto… - Journal of …, 1995 - thejns.org
… All glioma cell lines were maintained in tissue culture with Dulbecco’s modified Eagle’s …
human brain tissues and 17 human gliomas (A) as well as from five human glioma cell lines (GB-…

Tumor cell infiltration into the brain in glioblastoma: from mechanisms to clinical perspectives

F Seker-Polat, N Pinarbasi Degirmenci, I Solaroglu… - Cancers, 2022 - mdpi.com
glioblastoma cell invasion, including the routes followed by glioblastoma cells, the interaction
of tumor cells … Invasive glioblastoma cells diffusely infiltrate into normal brain tissue, which …

Transfection of glioma cells with the neural‐cell adhesion molecule NCAM: Effect on gliomacell invasion and growth in vivo

K Edvardsen, PH Pedersen, R Bjerkvig… - … journal of cancer, 1994 - Wiley Online Library
… migration and invasion into the surrounding normal brain tissue. A common feature of both
… BT4Cn glioma cells changed the growth characteristics of the tumors induced by these cells

[HTML][HTML] Downregulation of major histocompatibility complex antigens in invading glioma cells: stealth invasion of the brain

D Zagzag, K Salnikow, L Chiriboga, H Yee, L Lan… - Laboratory …, 2005 - Elsevier
… Invasion of glioma cells into surrounding brain tissue may be associated with at least two
processes, both of which defeat the immune surveillance mechanisms of the host: (i) …

The fatty acid composition of human gliomas differs from that found in nonmalignant brain tissue

DD Martin, MEC Robbins, AA Spector, BC Wen… - Lipids, 1996 - Springer
brain tissue. A reduction in the PUFA content of glioma cells relative to normal brain tissue
could contribute to the relative resistance of gliomas to therapy. This might provide the basis …

Effect of Epidermal Growth Factor on Glioma Cell Growth, Migration, and Invasion in Vitro

M Lund-Johansen, R Bjerkvig, PA Humphrey… - Cancer research, 1990 - AACR
… r in glioma cell invasiveness has not been studied. Here we report the effect of EGF on glioma
growth, glioma cell migration, and glioma … The propensity of gliomas to invade brain tissue

BEHAB (brain enriched hyaluronan binding) is expressed in surgical samples of glioma and in intracranial grafts of invasive glioma cell lines

DM Jaworski, GM Kelly, JM Piepmeier, S Hockfield - Cancer research, 1996 - AACR
… human glioma. We further show that glioma cell lines maintained under standard cell culture
… in situ, that is, that invade sur rounding normal brain tissue. The expression of BEHAB by in …

Expression of type VI collagen during glioblastoma cell invasion in brain tissue cultures

J Han, JC Daniel, GD Pappas - Cancer letters, 1995 - Elsevier
… , invading cells, and cell groups. We suggest that type VI collagen may be involved in tumor
cells infiltration and invasion of healthy rat brain tissues. Furthermore, the brain tissue culture …

BRG1 expression is increased in human glioma and controls glioma cell proliferation, migration and invasion in vitro

J Bai, PJ Mei, H Liu, C Li, W Li, YP Wu, ZQ Yu… - Journal of cancer …, 2012 - Springer
… microarray and immunohistochemistry, we evaluated BRG1 staining in 190 glioma tissues,
8 normal brain tissues and 8 tumor adjacent normal brain tissues. We studied glioma cell