NF-κB in cancer therapy

F Li, J Zhang, F Arfuso, A Chinnathambi, ME Zayed… - Archives of …, 2015 - Springer
… regulated by this transcription factor in cancer development and progression. Additionally, …
NF-κB signaling pathway, and their possible therapeutic potential in cancer therapy is also …

Is NF-κB a good target for cancer therapy? Hopes and pitfalls

V Baud, M Karin - Nature reviews Drug discovery, 2009 - nature.com
… evidence from cancer genetics and cancer genome studies … NF-κB in human cancer,
particularly in multiple myeloma. The therapeutic potential and benefit of targeting NF-κB in cancer, …

NFκB as a potential molecular target for cancer therapy

CH Lee, YT Jeon, SH Kim, YS Song - Biofactors, 2007 - Wiley Online Library
… Therefore, the inhibition of NF-κB activation and its signaling pathway offers a potential
cancer therapy strategy. In addition, recent studies have shown that NF-κB can also play a tumor …

NF-κB as a target for cancer therapy

D Melisi, PJ Chiao - Expert opinion on therapeutic targets, 2007 - Taylor & Francis
NF-κB. In this review, the authors discuss the rationale behind targeting NF-κB for cancer
therapy… of the NF-κB inhibitors alone and in combination with conventional chemotherapeutics. …

Targeting the NF-κB pathway in cancer therapy

DJ Erstad, JC Cusack - Surgical Oncology Clinics, 2013 - surgonc.theclinics.com
… inhibitors are reviewed, the challenges and shortcomings of targeting NF-κB are evaluated,
and the future directions for NF-κB inhibition in cancer therapy are presented. The NF-κB

Control of oncogenesis and cancer therapy resistance by the transcription factor NF-κB

AS Baldwin - The Journal of clinical investigation, 2001 - Am Soc Clin Investig
… radiation can blunt the ability of the cancer therapy to induce cell death. Below… NF-κB is
dysregulated in many forms of cancer and that its inhibition is a logical therapy for certain cancers

NF-κB as a target for pancreatic cancer therapy

C Carbone, D Melisi - Expert opinion on therapeutic targets, 2012 - Taylor & Francis
… to apoptosis, the activation of NF-κB can synergistically and effectively suppress the … cancer.
In this review, we discuss the rationale behind targeting NF-κB for pancreatic cancer therapy

NF-κB in the new era of cancer therapy

B Eluard, C Thieblemont, V Baud - Trends in cancer, 2020 - cell.com
… -edge therapies. This review aims to give an up-to-date view on the therapeutic potential of
NF-κB … and the signaling pathways that control their activity in the new era of cancer therapy. …

NFκB signaling in carcinogenesis and as a potential molecular target for cancer therapy

HM Shen, V Tergaonkar - Apoptosis, 2009 - Springer
… on the involvement of NFκB in cancer, by focusing on the role of NFκB in the carcinogenic …
NFκB inhibitors in cancer therapy. Biological functions of NFκB closely associated with cancer

The NF-κB activation pathways, emerging molecular targets for cancer prevention and therapy

Y Lin, L Bai, W Chen, S Xu - Expert opinion on therapeutic targets, 2010 - Taylor & Francis
… : NF-κB is involved in cancer development, modulating NF-κB activation … cancer prevention
and therapy. Due to the complexity of NF-κB roles in different cancers, careful evaluation of NF