… Thus, the benefits/consequences of therapeutic targeting of NF-κB have to be carefully evaluated.
… and consequences of NF-κB dysregulation in gastric cancer development and therapy. …

… Signaling pathways in cancer therapy Apoptosis in response to cancer therapy proceeds
through … While a number of initial studies suggested that cancer therapy–triggered apoptosis …

… the activation of NFκB in the hepatoma cell line HepG2 (Saliou et al., 1998) and in … therapy
is likely to be the most effective in combination with conventional cytotoxic cancer therapy…

… is correlated with tumor stage and response to therapy. Our results … cancer as well and also
suggests tumor subtype selection criteria for its therapeutic exploitation in cancer therapy. To …

… These diseases respond to anti-TNF therapy 48 , and the role of NF-κB in activating TNF …
inhibitors of NF-κB, which has raised enthusiasm about NF-κB and IKKβ as therapeutic targets …

… NF-κB protein and shows strong co-localisation with NF-κB in cell co-staining experiments.
Interestingly, in cancer cells, the platinum-bound active NF-κB … cancer cell by hijacking NF-κB …

… current therapies. The NF-κB signaling pathway plays critical roles in physiological and
pathological processes, and the relationship between colon cancer development and NF-κB is …

… Thus, inhibition of NF-κB has therapeutic potential in sensitization of tumors to … of NF-κB
can result in serious host toxicity with minimum effect on the tumor. Cancer Discovery; 1(6); 469–…

… cancer … NF-κB in signaling tumor resistance to radiotherapy. This review will discuss the
mechanisms of HER-2 mediated NF-κB signaling pathway and potential target for therapeutic …

… More recently, it has become obvious that inhibition of NF-κB activity is not only … in cancer
therapy. In a recent review, Michael Karin even described NF-κB as a major culprit in cancer [1]…