[HTML][HTML] Lack of predictive tools for conventional and targeted cancer therapy: Barriers to biomarker development and clinical translation

N Batis, JM Brooks, K Payne, N Sharma… - Advanced Drug Delivery …, 2021 - Elsevier
predictive tools to include all the above, but will focus on predictive omic biomarkers, predictive
… the current status of predictive tools for conventional and targeted therapy, highlighting …

Prognostic and predictive biomarkers: tools in personalized oncology

E Nalejska, E Mączyńska… - … diagnosis & therapy, 2014 - Springer
cancer patients respond to chemotherapeutics. Biomarkers detected using molecular biology
tools allow the molecular characterization of cancer … : prognostic and predictive. The aim of …

[HTML][HTML] Machine learning in the prediction of cancer therapy

R Rafique, SMR Islam, JU Kazi - Computational and Structural …, 2021 - Elsevier
… the basics of therapy response prediction and related ML … for monotherapy and combination
therapy in cancer treatment, a focus … Currently, only a few drug response prediction tools are …

[HTML][HTML] MicroRNAs: new biomarkers for diagnosis, prognosis, therapy prediction and therapeutic tools for breast cancer

G Bertoli, C Cava, I Castiglioni - Theranostics, 2015 - ncbi.nlm.nih.gov
Dysregulation of microRNAs (miRNAs) is involved in the initiation and progression of several
human cancers, including breast cancer (BC), as strong evidence has been found that …

An updated catalog of prostate cancer predictive tools

SF Shariat, PI Karakiewicz… - Cancer …, 2008 - Wiley Online Library
… In this review, we describe criteria for the evaluation of predictive tools and then catalogue
the current nomograms available for PCa according to the natural history of treated PCa. …

In Vitro Microtumors Provide a Physiologically Predictive Tool for Breast Cancer Therapeutic Screening

G Benton, G DeGray, HK Kleinman, J George… - PloS one, 2015 - journals.plos.org
Many anti-cancer drugs fail in human trials despite showing efficacy in preclinical models. It
is clear that the in vitro assays involving 2D monoculture do not reflect the complex …

Predicting cancer prognosis using interactive online tools: a systematic review and implications for cancer care providers

BA Rabin, B Gaglio, T Sanders, L Nekhlyudov… - Cancer epidemiology …, 2013 - AACR
… Prognostic tools have been developed to guide patient–physician communication and …
of prognostic tools, it is timely to review existing online cancer prognostic tools and discuss …

Molecular genetic tools shape a roadmap towards a more accurate prognostic prediction and personalized management of cancer

DH Roukos, S Murray, E Briasoulis - Cancer biology & therapy, 2007 - Taylor & Francis
… is a well established prognostic and predictive factor for breast cancer.Tamoxifen, the first
ever targeted cancer therapy, has saved thousands of lives of breast cancer patients and now …

Critical review of prostate cancer predictive tools

SF Shariat, MW Kattan, AJ Vickers, PI Karakiewicz… - Future …, 2009 - Taylor & Francis
… process of making decisions related to prostate cancer. In this review, we discuss attributes
of predictive tools and systematically review those available for prostate cancer. Types of …

Molecular circuits of solid tumors: prognostic and predictive tools for bedside use

C Ferté, F André, JC Soria - Nature reviews clinical oncology, 2010 - nature.com
… This knowledge has also generated a vast panel of cancer biomarkers although many of these
… /or predictive biomarkers in the six leading tumors with the highest contribution to cancer