… disease biomarkers largely remains to be explored. We have developed a novel workflow in
… CSF peptides and proteins by liquid chromatography coupled with mass spectrometry. After …

… workflow for the development of a novel enzyme-linked immunosortbent assay (ELISA).
Workflow … of assays for the validation of novel biomarker candidates. The process is divided into …

… Our data support the idea that the integration of complementary pathophysiological biomarker
candidates covering additional key AD mechanisms will likely result in an incremental …

… the strength of the biomarker candidate findings and their … The integrated ASAP 2 workflow
was applied to 96 identical … for biomarker discovery and that our ASAP 2 workflow can be …

… for a comprehensive search for novel diagnostic biomarkers. … extensive workflows and a
small number of candidates were … known biomarkers such as tau as top candidates as well as …

… Cerebrospinal fluid (CSF) is routinely collected in patients with neurological … workflow for
CSF proteome profiling. From two independent cohorts with over 200 individuals, our workflow …

… characterized candidate biomarkers by discovery proteomics analysis of cerebrospinal fluid
(… Taken together, we established a comprehensive strategy to discover and verify candidate …

… Several diagnostic protein biomarkers in body fluids are being used and implemented, … of
biomarkers for co-pathologies and other causes of dementia. Such biofluid-based biomarkers …

… workflow. We next thoroughly validated the results by (1) the same proteomic workflow in an
… These strengths make the current study the most comprehensive proteomic analysis in DLB …

… on a better understanding and integration of the systems biology … will consist of relevant
comprehensive panels of molecules … novel biomarkers: upcoming candidate cerebrospinal fluid …