Chronic cannabinoid administration in vivo compromises extinction of fear memory

HC Lin, SC Mao, PS Chen, PW Gean - Learning & Memory, 2008 - learnmem.cshlp.org
… The purpose of this study was to examine the effects of repeated cannabinoid administration
on the extinction of fear memory in rats. Such a study is important because of the …

The role of the cannabinoid system in fear memory and extinction in male and female mice

I Mizuno, S Matsuda, S Tohyama, A Mizutani - Psychoneuroendocrinology, 2022 - Elsevier
… of fear memory in male and female mice, we administered WIN before each contextual … the
retrieval and extinction of fear memory, we administered URB before each extinction session. …

The cannabinoid receptor agonist WIN 55,212-2 facilitates the extinction of contextual fear memory and spatial memory in rats

FA Pamplona, RDS Prediger, P Pandolfo… - …, 2006 - Springer
… study was to examine whether the administration of the cannabinoid agonist WIN 55,212-2
(… contextual fear memory in rats. Further, we investigated the role of the CB1 cannabinoid

Cannabinoid transmission in the basolateral amygdala modulates fear memory formation via functional inputs to the prelimbic cortex

H Tan, NM Lauzon, SF Bishop, N Chi… - Journal of …, 2011 - Soc Neuroscience
… to block the recall of olfactory fear memory when administered immediately after training, …
recall of olfactory fear memory in terms of conditioned exploratory behavior when administered

A time‐dependent contribution of hippocampal CB1, CB2 and PPARγ receptors to cannabidiol‐induced disruption of fear memory consolidation

AM Raymundi, TR da Silva… - British Journal of …, 2020 - Wiley Online Library
cannabinoid CB 1 and CB 2 , and 5-HT 1A receptors have been involved in the effects of CBD
on fear memory … the contextual fear memory consolidation when administered into the DH …

Cannabinoid facilitation of fear extinction memory recall in humans

CA Rabinak, M Angstadt, CS Sripada, JL Abelson… - …, 2013 - Elsevier
… hypotheses that administration of … cannabinoid modulators as an adjunctive strategy to
exposure-based therapies to augment extinction learning and prevent the return of fear memories

Learning and memory is modulated by cannabidiol when administered during trace fear-conditioning

AL Uhernik, ZT Montoya, CD Balkissoon… - … of Learning and Memory, 2018 - Elsevier
… CBD, in contrast, is a major cannabinoid which is not thought to be psychotropic and exerts
… formation of de novo fear memories if it were administered prior to memory acquisition. If true, …

Cannabinoid regulation of fear and anxiety: an update

EP Papagianni, CW Stevenson - Current psychiatry reports, 2019 - Springer
… of learned fear processing is mediated at least in part by cannabinoid receptor activation. …
its cannabinoid receptor-dependent effects on extinction and fear memory consolidation …

Effects of cannabinoid drugs on aversive or rewarding drug-associated memory extinction and reconsolidation

CAJ Stern, CR de Carvalho, LJ Bertoglio… - Neuroscience, 2018 - Elsevier
… ) and cannabinoid type-2 (CB 2 ) receptors in emotional memory … a closer look into certain
cannabinoid drugs owing to their … on extinction memory, it is usually administered prior to the …

Cannabidiol disrupts the consolidation of specific and generalized fear memories via dorsal hippocampus CB1 and CB2 receptors

CAJ Stern, TR da Silva, AM Raymundi, CP de Souza… - …, 2017 - Elsevier
… CBD had no effects on short-term fear memory, and its … fear memory specificity and
generalization, and cannabinoid type-1 (… the consolidation of different fear memories via …