Canonical WNT signaling during kidney development

DM Iglesias, PA Hueber, LL Chu… - American Journal …, 2007 - journals.physiology.org
… of canonical Wnt and/or Fz genes during renal development. … the specific sites of canonical
signaling activity to predict the … of canonical WNT signaling activity in developing kidney from …

Wnt signaling in kidney development and disease

Y Wang, CJ Zhou, Y Liu - Progress in molecular biology and translational …, 2018 - Elsevier
… As β-catenin is the principal intracellular mediator in canonical Wnt signaling, more
attentions have been paid to elucidate its roles during kidney development. Active form of β-catenin …

Non‐canonical wnt signals antagonize and canonical wnt signals promote cell proliferation in early kidney development

KE McCoy, X Zhou, PD Vize - Developmental Dynamics, 2011 - Wiley Online Library
… In this report, we use developing Xenopus embryos to demonstrate a novel anti-proliferative
role for non-canonical wnt signals in the very earliest stages of kidney development. Non-…

Wnt signaling in kidney development and disease

K Pulkkinen, S Murugan, S Vainio - Organogenesis, 2008 - Taylor & Francis
… The mechanism that may promote cystogenesis in the kidney at the cellular level may involve
not only changes in the canonical Wnt signaling but also alterations in cell adhesion and …

Tankyrase is necessary for canonical Wnt signaling during kidney development

CM Karner, CE Merkel, M Dodge, Z Ma… - Developmental …, 2010 - Wiley Online Library
canonical Wnt pathway (Huang et al.,2009). To determine if these factors had a role in kidney
development, … Kidney development initiates 11 days after fertilization when the ureteric bud …

Cystic kidney disease: the role of Wnt signaling

MA Lancaster, JG Gleeson - Trends in molecular medicine, 2010 - cell.com
… within the kidney. Both of these pathways are important for kidney development as well as
… Several cystic renal disease genes are linked to canonical Wnt signaling. The first evidence …

Primary cilia modulate balance of canonical and non-canonical Wnt signaling responses in the injured kidney

S Saito, B Tampe, GA Müller, M Zeisberg - Fibrogenesis & Tissue Repair, 2015 - Springer
… during kidney development, Wnt … non-canonical to canonical Wnt signaling may contribute
to the switch between physiological repair and pathological fibrogenesis in response to Wnt re…

Wnt/β-catenin signaling regulates nephron induction during mouse kidney development

JS Park, MT Valerius, AP McMahon - Development, 2007 - journals.biologists.com
… As a result of the depletion of the progenitor population, kidney development ceases at an
early stage. Our data here indicate that canonical Wnt signaling within the Six2 population …

Canonical Wnt9b signaling balances progenitor cell expansion and differentiation during kidney development

CM Karner, A Das, Z Ma, M Self, C Chen… - …, 2011 - journals.biologists.com
… To test whether the loss of the target genes can be specifically attributed to inhibition of the
canonical Wnt pathway, we cultured kidneys in the presence of IWR1. IWR1 administration …

Pygo1 and Pygo2 roles in Wnt signaling in mammalian kidney development

KR Schwab, LT Patterson, HA Hartman, N Song… - BMC biology, 2007 - Springer
… ) transcription factor complex of canonical Wnt signaling. To better understand the functions
of Pygopus-mediated canonical Wnt signaling in kidney development, targeted mutations …