[HTML][HTML] ceRNAs: miRNA target mimic mimics

I Rubio-Somoza, D Weigel, JM Franco-Zorilla… - Cell, 2011 - cell.com
miRNA targets (or mimics) would alter the ability of a miRNA to reduce the activity of other
… is the target mimicry principle, which endows nondegradable miRNA targets with regulatory …

ceRNAs in plants: computational approaches and associated challenges for target mimic research

AR Paschoal, I Lozada-Chávez… - Briefings in …, 2018 - academic.oup.com
miRNA targets and ceRNAs have highly similar miRNA-binding sites, often called … naturally
occurring endogenous target mimics (eTMs) and engineered artificial target mimics (aTMs). …

MicroRNAs and target mimics for crop improvement

PK Gupta - Current Science, 2015 - JSTOR
mimics, which are also descri bed as miRNA sponges or decoys. Artificial miRNA target mimics
… endogenous RNA (ceRNA) regulatory network (ceRNET)19'20 (for ceRNA and ceRNET, …

[HTML][HTML] Effective tools for RNA-derived therapeutics: siRNA interference or miRNA mimicry

P Wang, Y Zhou, AM Richards - Theranostics, 2021 - ncbi.nlm.nih.gov
… In conclusion, miRNA mimics have unique properties and … miRNA targeting. These issues
will be discussed in later sections. … (ceRNA) functions as a miRNA sponge to regulate miRNA

Cupid: simultaneous reconstruction of microRNA-target and ceRNA networks

HS Chiu, D Llobet-Navas, X Yang, WJ Chung… - Genome …, 2015 - genome.cshlp.org
… We used RPPA data to measure expression fold reduction of 120 proteins following
transfections of 159 miRNA mimics, including four mock controls, in MDA-MB-231 cells. We …

[HTML][HTML] Assessing the ceRNA hypothesis with quantitative measurements of miRNA and target abundance

R Denzler, V Agarwal, J Stefano, DP Bartel, M Stoffel - Molecular cell, 2014 - cell.com
miRNA target abundance is unlikely to cause significant effects on gene expression and
metabolism through a ceRNA … miR-33 were each expressed at fewer copies per cell (1.1 × 10 4 …

Competing endogenous RNA (ceRNA): a new class of RNA working as miRNA sponges

PK Gupta - Current Science, 2014 - JSTOR
… 'miRNA sponges/decoys', 'target mimics' or 'competing genous RNA '. Several reports of the
occurrence of these ceRNAs and … miRNA targets (later celled ceRNA) may be to sequester …

Mimicry, deception and competition: the life of competing endogenous RNAs

MP Grüll, E Massé - Wiley Interdisciplinary Reviews: RNA, 2019 - Wiley Online Library
… , and circular RNAs can act as ceRNAs for miRNAs. By sharing common MREs, they divert …
Every miRNA target contains at least one MRE, to which miRNAs can bind. The miRNAs bind …

ceRNA in cancer: possible functions and clinical implications

X Qi, DH Zhang, N Wu, JH Xiao, X Wang… - Journal of medical …, 2015 - jmg.bmj.com
… to extend the term ceRNA to include both miRNA targets and miRNA themselves. A … ceRNAs
as therapeutic targets. For example, artificial miRNA sponges containing multiple copies of …

Widespread long noncoding RNAs as endogenous target mimics for microRNAs in plants

HJ Wu, ZM Wang, M Wang, XJ Wang - Plant physiology, 2013 - academic.oup.com
… ) and engineered artificial RNAs can induce target mimicry effects. Yet … proven to be a
functional endogenous microRNA target mimic (eTM). In this … ceRNAs: miRNA target mimic mimics