… miRNAtargets and ceRNAs have highly similar miRNA-binding sites, often called … naturally occurring endogenous targetmimics (eTMs) and engineered artificial targetmimics (aTMs). …
… mimics, which are also descri bed as miRNA sponges or decoys. Artificial miRNAtargetmimics … endogenous RNA (ceRNA) regulatory network (ceRNET)19'20 (for ceRNA and ceRNET, …
P Wang, Y Zhou, AM Richards - Theranostics, 2021 - ncbi.nlm.nih.gov
… In conclusion, miRNAmimics have unique properties and … miRNAtargeting. These issues will be discussed in later sections. … (ceRNA) functions as a miRNA sponge to regulate miRNA …
… We used RPPA data to measure expression fold reduction of 120 proteins following transfections of 159 miRNAmimics, including four mock controls, in MDA-MB-231 cells. We …
… miRNAtarget abundance is unlikely to cause significant effects on gene expression and metabolism through a ceRNA … miR-33 were each expressed at fewer copies per cell (1.1 × 10 4 …
… 'miRNA sponges/decoys', 'targetmimics' or 'competing genous RNA '. Several reports of the occurrence of these ceRNAs and … miRNAtargets (later celled ceRNA) may be to sequester …
… , and circular RNAs can act as ceRNAs for miRNAs. By sharing common MREs, they divert … Every miRNAtarget contains at least one MRE, to which miRNAs can bind. The miRNAs bind …
X Qi, DH Zhang, N Wu, JH Xiao, X Wang… - Journal of medical …, 2015 - jmg.bmj.com
… to extend the term ceRNA to include both miRNAtargets and miRNA themselves. A … ceRNAs as therapeutic targets. For example, artificial miRNA sponges containing multiple copies of …
HJ Wu, ZM Wang, M Wang, XJ Wang - Plant physiology, 2013 - academic.oup.com
… ) and engineered artificial RNAs can induce targetmimicry effects. Yet … proven to be a functional endogenous microRNAtargetmimic (eTM). In this … ceRNAs: miRNAtargetmimicmimics …