… complex (MHC) on the surface of antigen-presenting cells or tumor cells. The first TCR T cellcancerimmunotherapy used in the clinic was tested against metastatic melanoma and …
RL Sabado, N Bhardwaj - Immunotherapy, 2010 - Taylor & Francis
The use of dendritic cells (DCs) for tumor immunotherapy represents a powerful approach for harnessing the patient‘s own immune system to eliminate tumor cells. However, …
K Perica, JC Varela, M Oelke… - Rambam Maimonides …, 2015 - ncbi.nlm.nih.gov
… and destroy tumor cells has been the central goal of anti-cancerimmunotherapy. In recent … feasible treatment. One of the main treatment modalities within cancerimmunotherapy has …
M Wang, B Yin, HY Wang, RF Wang - Immunotherapy, 2014 - Taylor & Francis
… and discuss future directions in adoptive cell transfer based cancerimmunotherapy. … T cells. In this review, we will highlight recent advances in ACT-based cancerimmunotherapy and …
PE Hughes, S Caenepeel, LC Wu - Trends in immunology, 2016 - cell.com
… combinations of targeted therapies and immunotherapies for the treatment of cancer. … By contrast, cancerimmunotherapies can elicit durable responses in subsets of treated patients …
C Hayes - Irish Journal of Medical Science (1971-), 2021 - Springer
… This review will focus on cellularimmunotherapies involving the use of T cells and natural killer (NK) cells in adoptive cell transfer, as well as briefly focussing on DC vaccines. …
P Zhang, Y Zhai, Y Cai, Y Zhao, Y Li - Advanced Materials, 2019 - Wiley Online Library
… treatment failure, as most drugs target cells of active proliferation. Immunotherapy has shown great potential in cancer … effector cells is less affected by the metabolic status of cancercells…
MS Mitchell - International immunopharmacology, 2003 - Elsevier
… as cancer chemotherapy began with the use of single agents and evolved into combination therapy, so immunotherapeutic … of CY and cancer vaccines such as autologous tumor cells, …
… In an effort to revert the functional anergy of NK cells within MHC-deficient tumors, we treated tumor-bearing mice with pro-inflammatory cytokines. Some mice received a combination of …