The T cell immune response against SARS-CoV-2

P Moss - Nature immunology, 2022 - nature.com
… of cellular responses against SARS-CoV-2 is likely to soon exceed those documented against
any other infection. … Following primary infection, the SARS-CoV-2-specific T cell response

Overview of immune response during SARS-CoV-2 infection: lessons from the past

VK Shah, P Firmal, A Alam, D Ganguly… - Frontiers in …, 2020 - frontiersin.org
… innate immune cells is impaired during SARS-CoV and MERS-CoV infection by … response
against SARS-CoV-2 has been found to be similar to that against other coronavirus infections

T cell response to SARS-CoV-2 infection in humans: A systematic review

M Shrotri, MCI van Schalkwyk, N Post, D Eddy… - PloS one, 2021 - journals.plos.org
… understanding of the cellular response to SARS-CoV-2 infection, specifically exploring the
role that T cell-mediated immunity might play in resistance to severe infection, clinical and …

Mapping and role of T cell response in SARS-CoV-2infected mice

Z Zhuang, X Lai, J Sun, Z Chen, Z Zhang… - Journal of Experimental …, 2021 - rupress.org
… T cell epitopes of SARS-CoV-2 identified in infected mice in this study were compared with
epitopes identified in SARS-CoV– and MERS-CoVinfected … cross-reactive T cell epitopes are …

Respiratory epithelial cell responses to SARS-CoV-2 in COVID-19

JP Bridges, EK Vladar, H Huang, RJ Mason - Thorax, 2022 - thorax.bmj.com
SARS-CoV-2 infection mechanisms and cellular responses. Primary cultured epithelia are
infected with SARS-CoV-2 and release a substantial amount of virus from the apical cell

T‐cell responses and therapies against SARSCoV2 infection

SM Toor, R Saleh, V Sasidharan Nair, RZ Taha… - …, 2021 - Wiley Online Library
… in the progression of COVID-19. Thus, better understanding of their roles in … responses to
SARS-CoV-2 infection is crucial. T cells primarily react to the spike protein on the coronavirus to …

SARS-CoV-2 pathogenesis

MM Lamers, BL Haagmans - Nature reviews microbiology, 2022 - nature.com
… -cell omics, organoid infection models and CRISPR screens. We describe how SARS-CoV-2
The first cells targeted by SARS-CoV-2 during natural infection in humans are likely to be …

T cell responses to SARS-CoV-2 spike cross-recognize Omicron

R Keeton, MB Tincho, A Ngomti, R Baguma, N Benede… - Nature, 2022 - nature.com
… We studied SARS-CoV-2-infected patients who were hospitalized with … antibodies, the
SARS-CoV-2 T cell responses generated upon vaccination or previous infection are highly cross-…

[HTML][HTML] Magnitude and dynamics of the T-cell response to SARS-CoV-2 infection at both individual and population levels

TM Snyder, RM Gittelman, M Klinger, DH May… - MedRxiv, 2020 - ncbi.nlm.nih.gov
… Moreover, a collection of public SARS-CoV-2 TCRs form a … past infection of SARS-CoV-2.
We report initial findings that the T-cell response is durable for at least 3 months after infection, …

Acute SARS-CoV-2 infection impairs dendritic cell and T cell responses

R Zhou, KKW To, YC Wong, L Liu, B Zhou, X Li… - Immunity, 2020 - cell.com
… , yet the role of host immune responses in early COVID-19 … acute SARS-CoV-2 infection
resulted in broad immune cell reduction including T, natural killer, monocyte, and dendritic cells (…