[HTML][HTML] Automated methods for cell type annotation on scRNA-seq data

G Pasquini, JER Arias, P Schäfer… - Computational and …, 2021 - Elsevier
… of the cellular heterogeneity and dynamics. Cell type annotation is a crucial step in analyzing
single-cell RNA sequencing data, yet manual annotation is time-consuming and partially …

[HTML][HTML] Transformer for one stop interpretable cell type annotation

J Chen, H Xu, W Tao, Z Chen, Y Zhao… - Nature …, 2023 - nature.com
… In this study, we develop and establish TOSICA, a Transformer-based cell type annotation
cell type annotations under many scenarios, including but not limited to new cell type

Evaluation of cell type annotation R packages on single-cell RNA-seq data

Q Huang, Y Liu, Y Du, LX Garmire - Genomics, Proteomics and …, 2021 - academic.oup.com
… ten cell type annotation methods publicly available as R packages. Eight of them are popular
methods developed specifically for single-cell … among cell types, and increased cell type

[HTML][HTML] SCSA: a cell type annotation tool for single-cell RNA-seq data

Y Cao, X Wang, G Peng - Frontiers in genetics, 2020 - frontiersin.org
… an excellent and unbiased performance on cell type annotation with a desirable precision. …
five annotated cell types (monocytes cells, T cells, NK cells, megakaryocytes cells, and B cells)…

[HTML][HTML] scBERT as a large-scale pretrained deep language model for cell type annotation of single-cell RNA-seq data

F Yang, W Wang, F Wang, Y Fang, D Tang… - Nature Machine …, 2022 - nature.com
… model, single-cell bidirectional encoder representations from … then transferred to the cell type
annotation task of unseen and … of scBERT on cell type annotation, novel cell type discovery, …

Cell type annotation of single-cell chromatin accessibility data via supervised Bayesian embedding

X Chen, S Chen, S Song, Z Gao, L Hou… - Nature Machine …, 2022 - nature.com
… between real cell type labels and cell types annotated by EpiAnno (… annotated 96.2% of
EX, MG, AC and OC cells, but annotated some IN cells as EX cells because these two cell types

scDeepSort: a pre-trained cell-type annotation method for single-cell transcriptomics using deep learning with a weighted graph neural network

X Shao, H Yang, X Zhuang, J Liao, P Yang… - Nucleic acids …, 2021 - academic.oup.com
… of cells in a single assay based on transcriptome profiling. In most analysis protocols, single-cell
type annotation … Still, the accurate cell-type annotation for single-cell transcriptomic data …

[PDF][PDF] scCATCH: automatic annotation on cell types of clusters from single-cell RNA sequencing data

X Shao, J Liao, X Lu, R Xue, N Ai, X Fan - Iscience, 2020 - cell.com
type identification is critical for mechanistic studies. In most current analysis protocols, cell
type-based cluster annotation … , resulting in poor replicability of cell type annotation. This study …

Joint cell segmentation and cell type annotation for spatial transcriptomics

R Littman, Z Hemminger, R Foreman… - Molecular systems …, 2021 - embopress.org
… Using the cell type annotations from the single-cell data, we trained a DNN to classify cell
types. As expected, our classifier derived a cell type mapping agreeing with known spatial …

Deep learning does not outperform classical machine learning for cell-type annotation

ND Köhler, M Büttner, FJ Theis - BioRxiv, 2019 - biorxiv.org
… be used for cell annotation, ie to predict cell-type labels from single-cell gene expression …
Thus, cell-type prediction based on gene-signature derived cell-type labels is potentially too …