… elements in heterogeneous populations of primary cells. Our findings provide insights into cell-type-specific gene expression patterns in the developinghumancortex and advance our …
… Alternative splicing is prevalent in the mammalian brain. To interrogate … development, we analyzed purified neural progenitor cells (NPCs) and neurons from developingcerebralcortices…
BG Rash, EA Grove - Current opinion in neurobiology, 2006 - Elsevier
… Second, neocortex is composed of layers that organize cortical connectivity. Recent studies of layer and area development have used time-lapse microscopy to follow corticalcell …
… Recent advances in molecular profiling, including those with single-cell resolution, have … mechanisms of cortical arealization with a particular focus on humancorticaldevelopment, …
… cell regulatory atlas of the developinghumancerebralcortex To capture cellular heterogeneity in the cerebralcortex… Genomics) to generate single-cell assay for transposase-accessible …
N Zecevic, Y Chen, R Filipovic - Journal of Comparative …, 2005 - Wiley Online Library
… nestin + cells, with other celltypes … of cells (∼10%) are generated in the humancortical SVZ during midgestation (18–24 gw) under in vitro conditions. Immunofluorescence with celltype…
… humancortex enabled the identification of different cell populations and their candidate regulatory elements in the developingcortex ( … between these celltypes and cerebral organoids. …
… celltypes, with a marked distinction between PNs and INs. In the attempt of addressing the `celltype’ definition in the cerebralcortex, … unequivocally between a cellulartype or state is of …
… in the mouse represent an approximation of what we may discover to be relevant to human brain function during development and in the presence of disease. For example, studies in …