New insights into the development of the human cerebral cortex

Z Molnár, GJ Clowry, N Šestan, A Alzu'bi… - Journal of …, 2019 - Wiley Online Library
… Additional subtypes of radial glia have been described in the developing human cortex, …
important experimental platforms for cell-type discovery in the developing human cortex. …

Cell-type-specific 3D epigenomes in the developing human cortex

M Song, MP Pebworth, X Yang, A Abnousi, C Fan… - Nature, 2020 - nature.com
… elements in heterogeneous populations of primary cells. Our findings provide insights into
cell-type-specific gene expression patterns in the developing human cortex and advance our …

[HTML][HTML] Cell-type-specific alternative splicing governs cell fate in the developing cerebral cortex

X Zhang, MH Chen, X Wu, A Kodani, J Fan, R Doan… - Cell, 2016 - cell.com
… Alternative splicing is prevalent in the mammalian brain. To interrogate … development, we
analyzed purified neural progenitor cells (NPCs) and neurons from developing cerebral cortices

Area and layer patterning in the developing cerebral cortex

BG Rash, EA Grove - Current opinion in neurobiology, 2006 - Elsevier
… Second, neocortex is composed of layers that organize cortical connectivity. Recent
studies of layer and area development have used time-lapse microscopy to follow cortical cell

[PDF][PDF] Development and arealization of the cerebral cortex

CR Cadwell, A Bhaduri, MA Mostajo-Radji, MG Keefe… - Neuron, 2019 - cell.com
… Recent advances in molecular profiling, including those with single-cell resolution, have …
mechanisms of cortical arealization with a particular focus on human cortical development, …

[HTML][HTML] Chromatin and gene-regulatory dynamics of the developing human cerebral cortex at single-cell resolution

AE Trevino, F Müller, J Andersen, L Sundaram… - Cell, 2021 - Elsevier
cell regulatory atlas of the developing human cerebral cortex To capture cellular heterogeneity
in the cerebral cortex… Genomics) to generate single-cell assay for transposase-accessible …

Contributions of cortical subventricular zone to the development of the human cerebral cortex

N Zecevic, Y Chen, R Filipovic - Journal of Comparative …, 2005 - Wiley Online Library
… nestin + cells, with other cell types … of cells (∼10%) are generated in the human cortical
SVZ during midgestation (18–24 gw) under in vitro conditions. Immunofluorescence with cell type

[HTML][HTML] Massively parallel characterization of psychiatric disorder-associated and cell-type-specific regulatory elements in the developing human cortex

C Deng, S Whalen, M Steyert, R Ziffra, PF Przytycki… - bioRxiv, 2023 - ncbi.nlm.nih.gov
human cortex enabled the identification of different cell populations and their candidate
regulatory elements in the developing cortex ( … between these cell types and cerebral organoids. …

Decoding neuronal diversity in the developing cerebral cortex: from single cells to functional networks

S Mancinelli, S Lodato - Current opinion in neurobiology, 2018 - Elsevier
cell types, with a marked distinction between PNs and INs. In the attempt of addressing the
`cell type’ definition in the cerebral cortex, … unequivocally between a cellular type or state is of …

Shared and derived features of cellular diversity in the human cerebral cortex

DJ Miller, A Bhaduri, N Sestan, A Kriegstein - Current opinion in …, 2019 - Elsevier
… in the mouse represent an approximation of what we may discover to be relevant to human
brain function during development and in the presence of disease. For example, studies in …