… the differences between measures, neglecting the extent of shared information in these
measures that may be leveraged to improve our ability to uncover their genetic architectures. …

… To identify genetic loci and understand the genetic architecture of IR, we performed
GWAS analysis with $200,000 high-quality single-nucleotide polymorphisms (SNPs) spaced …

… function of the cell. Here, we review how currently known PD-linked genetic variants may …
to the graded risk concept representing the complex genetic architecture of PD (Fig. 1) and …

… genes with widespread effects on CNS structures is still difficult, because QTL can often
have pleiotropic and differential effects on many brain regions and cell types. Such genes may …

… in DNA repair and cell cycle regulation. This canonical oncogenic module gathered most of
the childhood cancer predisposition genes and clinically actionable genes. In pediatric acute …

… This paper explores the genetic architectures of a number of common disease conditions
and complex traits, as revealed by the most important SNPs used in genomic predictors. …

… co-expressed genes are enriched for certain cellular functions. One of the major breakthroughs
in our understanding of cellular networks was finding that cellular networks display scale-…

… ‘‘genetic architecture’’ of psychiatric disorders and the challenges of using these findings to
inform our understanding of pathophysiology. Genetic architecture … of genetic architecture is …

… genetic architecture … Genetic architecture and risk scores By increasing the number of
European-origin psoriasis susceptibility loci to 63, we were able to explore the genetic architecture …

… the genetic architecture of seven ADs in terms of genetic correlation, tissue and cell specificity,
… We revealed the high heritability and strong genetic correlations among seven ADs. The …