Cellular mechanisms of atherogenesis

PWF Wilson, JC Evans - American journal of hypertension, 1993 - academic.oup.com
… in human atherogenesis, or in any animal model of atherosclerosis, remains to be rigorously
defined. One reason for the lack of information regarding the in vivo situation is the transient …

The process of atherogenesiscellular and molecular interaction: from experimental animal models to humans

R Ross, L Agius - Diabetologia, 1992 - Springer
… Although hypercholesterolaemia is a major risk factor in human atherogenesis, the
commonly studied rodent models do not develop atherosclerotic lesions in response to …

Cellular mechanisms of human atherogenesis: focus on chronification of inflammation and mitochondrial mutations

AM Markin, IA Sobenin, AV Grechko, D Zhang… - Frontiers in …, 2020 - frontiersin.org
… However, despite the constant progress, our understanding of the mechanisms of atherogenesis
is still incomplete. One of the remaining puzzles in atherosclerosis development is the …

Cellular mechanisms in the development of atherosclerosis

ME Rosenfeld - Diabetes research and clinical practice, 1996 - Elsevier
… studies of the atherogenic process in hypercholesterolemic swine, monkeys and rabbits [1-4]
first demonstrated that the earliest observable cellular event in the atherogenic process is …

Cellular adhesion molecules and atherogenesis 1

DT Price, J Loscalzo - The American journal of medicine, 1999 - amjmed.com
… Our understanding of the process of atherogenesis has evolved … Evidence for the role of
chronic inflammation in atherogenesis … molecules in atherogenesis are the focus of this review. …

A modern view of atherogenesis

CJ Schwartz, AJ Valente, EA Sprague - The American journal of cardiology, 1993 - Elsevier
… As our understanding of the mechanisms involved in the pathogenesis of atherosclerosis
has evolved over the past few years, novel strategies for intervention in the atherogenic

Changing concepts of atherogenesis

P Libby - Journal of internal medicine, 2000 - Wiley Online Library
… and cellular events. As we enhance our understanding of its fundamental mechanisms, we
can begin to approach atherogenesis … Eventually, mastery of the cell and molecular biology of …

Pathophysiology of the atherogenic process

CJ Schwartz, JL Kelley, RM Nerem, EA Sprague… - The American journal of …, 1989 - Elsevier
… Conceptually, we may appropriately consider atherogenesis holistically as the result of … is
an important question in the pathophysiology of atherogenesis. In the same context, it also is …

Atherogenesis—recent insights into basic mechanisms and their clinical impact

V Schächinger, AM Zeiher - Nephrology Dialysis …, 2002 - academic.oup.com
… Prior to the development of atherosclerotic plaques, endothelial vasodilator function is
impaired early in the process of atherogenesis. The endothelium is not only a single cell layered …

Mechanisms of foam cell formation in atherosclerosis

DA Chistiakov, AA Melnichenko… - Journal of molecular …, 2017 - Springer
… in pro-atherogenic vascular … atherogenic agent, induces foam formation and monocyte
adhesion via inducing expression of acetyl-CoA acetyltransferase (ACAT)1 and vascular cell