… The role of PDGFR-β in NSPCs was suggested to be age dependent in mice, and remains …
brain. Here, we hypothesize that PDGFR-β may induce nerve tissue regeneration after stroke …

… Thus, the PDGFR-β signal is supposed to promote integrated cellular responses among
these cell types after cerebral stroke; however, its functional relevance largely remains elusive …

… receptor β (PDGFRβ) … brain barrier (BBB) and in the repair process in infarct areas. The aim
of this study was to uncover how the PDGFRβ expression is regulated in pericytes after brain …

… Platelet-derived growth factor receptor β (PDGFRβ)-expressing pericytes are responsible
for post-stroke fibrotic repair within infarct areas; therefore, we examined peri-infarct neural …

… PDGFR signaling in brain pericytes after ischemic stroke. In a rat middle cerebral artery
occlusion (MCAO) model, PDGFR … in the pericytes in peri-infarct areas and its level was gradually …

… and -β in preclinical studies including models of stroke [26,27,… stroke experiments on mutant
mice with conditional Pdgfra … lesions in the acute and subacute phases of stroke, in line with …

… is a contributing factor to brain injury in many diseases, including stroke. Increased … stroke,
resulting in pericyte dysfunction, swollen astrocytic end-feet, and may contribute to cerebral …

… 生命・臨床医学専攻 学位論文題目 PDGFR-β plays a key role in the ectopic migration of
neuroblasts in cerebral stroke (血小板由来増殖因子β受容体は脳梗塞後にみられる神経芽細胞 の異所…

… PDGFRβ signaling may be necessary to minimize the infarct volume and elicit prompt repair
processes after ischemic stroke, … of fibrosis after ischemic stroke will be needed in the future. …

… crenolanib is more selective for inhibiting PDGFRα/β than imatinib. We found that 3 days of
… However, our data strongly suggest that PDGFR inhibition after acute ischemic stroke needs …