… cerebral vasculature contribute to disease pathology and cognitive decline in Alzheimer's
disease … We also discuss how changes to the cerebral vasculature are likely to impair Aβ …

… vessels, the perfusion rate of the brain can considerably decrease causing directly or
through structural vascular damage a drop in cerebral glucose utilization. Consequently, …

… that Alzheimer's disease (AD) is primarily a vascular disorder… linking vascular risk factors
to cerebrovascular pathology that … in Alzheimer brains; (2) evidence that AD and vascular …

… Here, we describe the characteristic age-dependent alterations in cerebral vasculature of
APP23 transgenic (tg) mice, which display typical pathological hallmarks of the …

… as apolipoprotein E in relation to cerebrovascular lesions that may shed light on the
pathophysiology of the cerebral vasculature. The compelling vascular pathology associated with AD …

… Changes of the cerebral vasculature are triggered and driven by systemic … cerebral vessels
might have systemic effects. We know that many brain diseases are associated with vascular …

… Finally, we examine the interface between Alzheimer’s disease and vascular dementia
and how age changes in the microvasculature have an impact on current therapies for …

… The cerebral vasculature plays an essential role in the physiology of the central nervous
system (CNS). It is responsible for the delivery of oxygen and nutrients to the brain, the …

… The Alzheimer type of dementia and … that vascular risk factors linked to cerebrovascular
disease and stroke in the elderly significantly increase the risk of developing Alzheimer’s disease …

… Increasing evidence points to non-structural vascular dysfunction rather than structural
abnormalities of vessel walls as the main cause of cerebral hypoperfusion in AD. Several …