The cytokine storm in COVID-19: An overview of the involvement of the chemokine/chemokine-receptor system

F Coperchini, L Chiovato, L Croce, F Magri… - Cytokine & growth factor …, 2020 - Elsevier
… Available evidence indicate that the so called “cytokine stormChemokines are low molecular
weight proteins with powerful … chemokine/chemokine-receptor system in the cytokine storm

The cytokine storm in COVID-19: Further advances in our understanding the role of specific chemokines involved

F Coperchini, L Chiovato, G Ricci, L Croce… - Cytokine & Growth …, 2021 - Elsevier
chemokine/chemokine receptor system largely contributed to the onset of the “cytokine storm
on the topic of chemokine involvement in COVID-19-related cytokine storm, it has become …

Cytokine storm in COVID‐19 patients, its impact on organs and potential treatment by QTY code‐designed detergent‐free chemokine receptors

MI Mustafa, AH Abdelmoneim… - Mediators of …, 2020 - Wiley Online Library
… lungs through cytokine storms, … cytokine storm in COVID-19 patients, their impact on the
organs, and the potential treatment by QTY code-designed detergent-free chemokine receptors

Targeting the “cytokine storm” for therapeutic benefit

RV D'Elia, K Harrison, PC Oyston… - Clinical and Vaccine …, 2013 - Am Soc Microbiol
… We review some of the current candidates for treatment of cytokine storms which …
chemokines/chemokine receptors has proved challenging. This is predominantly due to the …

[PDF][PDF] CXCL10 an important chemokine associated with cytokine storm in COVID-19 infected patients.

N Zhang, YD Zhao, XM Wang - European Review for Medical & …, 2020 - europeanreview.org
cytokine storm in COVID-19 infected patients is not clear. This study aims to identify the key
genes that cause cytokine storm … the key chemokine CXCL10 that causes the cytokine storm. …

Targeting inflammation and cytokine storm in COVID-19

Q Huang, X Wu, X Zheng, S Luo, S Xu… - Pharmacological Research, 2020 - Elsevier
… the involvement of a cytokine storm [2]. Cytokine storm represents an exaggerated immune
… of pro-inflammatory cytokines and chemokines such as IFN-γ, TNF-α, IL-6, IL-1β, IL-18, …

The cytokine storm and COVID‐19

B Hu, S Huang, L Yin - Journal of medical virology, 2021 - Wiley Online Library
… the cytokine storm induced by COVID-19. In addition, we suggest that the identification and
treatment of the cytokine storm … and chemokines, including vascular endothelial growth factor, …

Into the eye of the cytokine storm

JR Tisoncik, MJ Korth, CP Simmons… - Microbiology and …, 2012 - Am Soc Microbiol
… However, dampening an overactive proinflammatory response is not as straightforward
as targeting the key cytokine mediators, since most chemokine receptors, for example, bind …

Role of toll‐like receptors in modulation of cytokine storm signaling in SARS‐CoV‐2‐induced COVID‐19

M Manik, RK Singh - Journal of medical virology, 2022 - Wiley Online Library
… is observed in the blood, including cytokines like interleukin (IL)‐2, IL‐4, IL6, IL‐1β, IL‐8, …
IL6 and IL‐1β are one of the driving factors for bringing the cytokine storm into the systemic …

Cytokines and chemokines in SARS-CoV-2 infections—therapeutic strategies targeting cytokine storm

A Pum, M Ennemoser, T Adage, AJ Kungl - Biomolecules, 2021 - mdpi.com
chemokines can activate more than one receptor and some receptors can be activated by
more than one chemokine… to the typical GPCR chemokine receptors, chemokines also bind …