… dysfunction and increased vessels permeability. We discuss here the direct role of blood–brain
barrier (BBB) dysfunction in epileptogenesis and brain … presence of dysfunctional BBB, …

… brain connection is currently being experimentally explored in the context of different human
CNS disorders… stress, and reinforce the intestinal barrier and blood-brain barrier (BBB) (20,…

… the brain without disrupting the blood-brain barrier (BBB) and permit substances that do not
cross the BBB to trigger changes in the brain … dysfunction and activates microglia in the brain …

… These findings have led to speculations about the role of gastrointestinal dysfunction in the
early pathophysiology of the disease6,7. It has been conjectured that an ingested neurotoxin …

… In summary, aging and tau protein induce the same bioenergetic impairments in the brain,
namely mitochondrial dysfunction and increased oxidative damage. In addition, age-related …

… benefits not only from chicken eggs but also egg-derived bio… activity results in impairment
of brain function. Among the … of blood-brain barrier integrity and brain health. Gut Microbes, …

… have been detected in human cerebral arteries (see [7]); in … Impairment and slowing of
perivascular drainage is associated with the formation of fibrillar amyloid in the walls of cerebral …

… free (SPF) chicken eggs. Allantoic fluid was titrated in SPF eggs according to the method of
Reed and Muench [22] and later diluted in PBS to obtain a dose of 10 6 egg lethal dose 50% (…

… and neuronal dysfunction. Another feature associated with neuroinflammatory diseases is
impairment of the blood-brain barrier (BBB). The BBB, which is composed of brain endothelial …

… The blood-brain barrier (… -brain barrier protects the brain from circulating neurotransmitters
as well as from many toxins. Considering the pivotal role the BBB plays in maintaining brain …