COVID-19 and preexisting comorbidities: risks, synergies, and clinical outcomes

B Bigdelou, MR Sepand, S Najafikhoshnoo… - Frontiers in …, 2022 - frontiersin.org
… In diabetes mellitus, a delay in the onset of adaptive immunity and dysregulation of the
cytokine response can involve the onset of cytokine storm. (Patients with diabetes mellitus are …

Platelets in the NETworks interweaving inflammation and thrombosis

AK Wienkamp, L Erpenbeck, J Rossaint - Frontiers in Immunology, 2022 - frontiersin.org
… Here, virus infiltration may lead to a cytokine storm that potently activates neutrophils and
leads to massive neutrophil infiltration into the lung and NET formation. The resulting NETs …

Guardians Turned Culprits: NETosis and Its Influence on Pulmonary Fibrosis Development

A Varughese, A Balnadupete, P Ramesh… - Molecular …, 2024 - Springer
… The chief components of the NETs include DNA, citrullinated histones, and anti-microbial
peptides which are released by the activated neutrophils. However, it is becoming increasingly …

[PDF][PDF] Demographic and Laboratory Parameters among Covid-19 Outpatients Versus and Hospitalized Patients

GD Dhumad, HS Kadhim, HA Shamran… - Pakistan Journal of …, 2022 - academia.edu
… most likely due to a cytokine storm (1-4).Differentially expressed cytokines are produced at
sites … IL-6 is a significant pro-inflammatory mediator (3) with a chief role in the host's defense …

Atypical presentations in COVID-19-lung abscess, pulmonary thromboembolism and ST-elevation myocardial infarction: diagnosis and management in a temporary …

P Harikrishnan, S Mohakuda, B Pathak… - Journal of Marine …, 2020 - journals.lww.com
… , with no prior comorbidities had presented with chief complaints of fever and cough with …
replication, which is worsened by consequent cytokine storm and inflammatory damage.[ 14 ] …

Early initiation of extracorporeal blood purification using the AN69ST (oXiris®) hemofilter as a treatment modality for COVID-19 patients: a single-centre case series

P Ugurov, D Popevski, T Gramosli, D Neziri… - Brazilian Journal of …, 2021 - SciELO Brasil
IL-6 is the primary cytokine leading to hepatic CRP … was associated with stable or decreasing
levels of IL-6, IL-8, and TNF-α … Successful recovery of severe COVID-19 with cytokine storm

Uncovering the information immunology journals transmitted for COVID-19: A bibliometric and visualization analysis

J Zhao, J Zhu, C Huang, X Zhu, Z Zhu, Q Wu… - Frontiers in …, 2022 - frontiersin.org
… , natural killer cells and dendritic cells into a cytokine storm (136). In addition, the IL-12 …
Cytokine storm is strongly associated with fatal outcomes in patients with severe COVID-19 (…

[PDF][PDF] COVID-19: an immunologist's perspective

S Yadav, N Challagundla, D Shah, P Dalai, H Vora… - NATURAL SCIENCES - iar.ac.in
… inflammatory cytokines mediate pathogenic cytokine storm in … IL-1 could also be called
the chief cytokine of local and … one of the culprit in inducing cytokine storm and septic shock…

Inflammasomes: a rising star on the horizon of COVID-19 pathophysiology

M Wang, F Yu, W Chang, Y Zhang, L Zhang… - Frontiers in …, 2023 - frontiersin.org
cytokine storm and hyperinflammation. NLRP3 has been detected in various cell types,
including innate immune cells, lung epithelial cells and cardiac cells (52). It is thus inferred that …

[PDF][PDF] Combating the challenges of COVID-19 pandemic: Insights into molecular mechanisms, immune responses and therapeutics against SARS-CoV-2

K Negi, M Agarwal, I Pahuja, B Bhardwaj… - Oxford Open …, 2023 - academic.oup.com
… SARS-CoV-2 has been the chief source of threat to public health and safety … , cytokine storm
is elicited which results in inflammation of the lung. Cytokine storm and upsurge of cytokines