… ageacceleration assessed using the DNAm GrimAge and DNAm PhenoAge in middle and older-aged adults in … to ACEs would be associated with epigenetic ageacceleration in adults. …
… Adverse childhoodexperiences (ACEs) increase risk for depression at subsequent ages and have been linked to accelerated biological aging. We hypothesize that accelerated …
… As childhood BMI may be an important contributor to age at menarche, we recommend that future research on the effects of early life trauma through pubertal timing include prepubertal …
… We examine the association of ELA ageacceleration in mid-life using the next-generation … If we assume that the effects of childhood poverty on ageacceleration are causal, how is it that …
… age comparing participants with 4 or more vs less than 4 adverse childhoodexperiences. … ACEs was consistently associated with various epigenetic ageacceleration measurements. …
CK Dye, DM Alschuler, H Wu, C Duarte… - JAMA Network …, 2024 - jamanetwork.com
… Main Outcomes and Measures Changes in epigenetic ageacceleration (EAA) were investigated as the primary outcome in maternal models during pregnancy. Changes in epigenetic …
… Although not statistically significant, similar trends of ageacceleration were observed in … Like studies of ACEs experienced directly by children, we observe epigenetic ageacceleration …
G Yang, X Cao, X Li, J Zhang, C Ma, N Zhang… - JAMA network …, 2022 - jamanetwork.com
… This study aimed to examine the associations of childhood adversity with phenotypic age acceleration, as well as the role of unhealthy lifestyle as a mediator in the associations. …
… Accelerated epigenetic age was also associated with a more … that advanced epigenetic aging during childhood may be one … associated with epigenetic ageacceleration in our sample, …