Chitosan nanoparticles as a mucoadhesive drug delivery system for ocular administration

MM Silva, R Calado, J Marto, A Bettencourt… - Marine drugs, 2017 - mdpi.com
… release profile from the chitosan/TPP-hyaluronic acid nanoparticles gel formulation. …
chitosan/TPP-hyaluronic acid nanoparticle eye drop formulations are a promising platform for ocular

Chitosan nanoparticles: a new vehicle for the improvement of the delivery of drugs to the ocular surface. Application to cyclosporin A

AM De Campos, A Sánchez, MJ Alonso - International journal of …, 2001 - Elsevier
… In the present study, the potential of chitosan (CS) nanoparticles as a new vehicle for the
improvement of the delivery of drugs to the ocular mucosa was investigated. Cyclosporin A (CyA…

Chitosan nanoparticles for ocular delivery of cyclosporine A

E Başaran, E Yenilmez, MS Berkman… - Journal of …, 2014 - Taylor & Francis
… In this study, incorporation of CsA into cationic chitosan nanoparticles was planned with an
attempt to increase the ophthalmic contact time of CsA with the help of molecular attraction of …

Chitosan nanoparticles for drug delivery to the eye

P Paolicelli, M de la Fuente, A Sanchez… - Expert Opinion on …, 2009 - Taylor & Francis
… the in vivo behaviour of chitosan nanoparticles (CS NP) as ocular delivery systems for the
treatment … The interesting features of chitosan nanoparticles for ocular administration of drugs …

[HTML][HTML] Chitosan nanoparticles as a potential drug delivery system for the ocular surface: toxicity, uptake mechanism and in vivo tolerance

AE de Salamanca, Y Diebold, M Calonge… - … & visual science, 2006 - arvojournals.org
Administration of drug-loaded chitosan-based nanoparticles improved both insulin 11 and
tetanus toxoid 12 27 transport across the nasal epithelium in mice. With those results in mind, …

Development and evaluation of chitosan nanoparticles for ocular delivery of tedizolid phosphate

MA Kalam, M Iqbal, A Alshememry, M Alkholief… - Molecules, 2022 - mdpi.com
chitosan-nanoparticles (CSNPs) for ocular delivery of tedizolid phosphate (TZP) for the
treatment of MRSA-related ocular … After topical administration, the ocular availability of drugs is …

The potential of chitosan in ocular drug delivery

MJ Alonso, A Sánchez - Journal of pharmacy and …, 2003 - Wiley Online Library
… Most of the reports on the topical ocular administration of chitosan … with chitosan nanoparticles.
Therefore, the conclusions from this study were that the stability of chitosan nanoparticles

Pharmacokinetic and pharmacodynamic evaluation of gemifloxacin chitosan nanoparticles as an antibacterial ocular dosage form

HAFM Hassan, AI Ali, EM ElDesawy… - Journal of …, 2022 - Elsevier
… the chitosan NPs to promote the antibacterial activity of GM against eye infections via ocular
administration. … In this study, we assessed the chitosan NP's ability to enhance the efficacy of …

Chitosan Nanoparticles as New Ocular Drug Delivery Systems: in Vitro Stability, in Vivo Fate, and Cellular Toxicity

AM de Campos, Y Diebold, ELS Carvalho… - Pharmaceutical …, 2004 - Springer
… To assess the potential of chitosan (CS) nanoparticles for ocular drug delivery by investigating
their interaction with the ocular mucosa in vivo and also their toxicity in conjunctival cell …

Bioadhesive hyaluronan–chitosan nanoparticles can transport genes across the ocular mucosa and transfect ocular tissue

M De la Fuente, B Seijo, MJ Alonso - Gene therapy, 2008 - nature.com
… In addition, we observed that, following topical administration to rabbits, these nanoparticles
entered the corneal and conjunctival epithelial cells and, then, become assimilated by the …