Formulation and optimization of levofloxacin loaded chitosan nanoparticle for ocular delivery: In-vitro characterization, ocular tolerance and antibacterial activity

SS Imam, SNA Bukhari, J Ahmad, A Ali - International journal of …, 2018 - Elsevier
… In this study, chitosan nanoparticles (CH-NPs) were used to encapsulate antibacterial agent
chitosan nanoparticles in situ gel system found to be an efficient carrier for ocular delivery of …

Chitosan nanoparticles amplify the ocular hypotensive effect of cateolol in rabbits

J Ali, A Bhatnagar, N Kumar, A Ali - International journal of biological …, 2014 - Elsevier
… To assess the potential of chitosan (CS) nanoparticles for ocular drug delivery by
investigating their intraocular retention by γ-scintigraphy and intraocular pressure reduction. …

Chitosan coated sodium alginate–chitosan nanoparticles loaded with 5-FU for ocular delivery: In vitro characterization and in vivo study in rabbit eye

RC Nagarwal, R Kumar, JK Pandit - European Journal of Pharmaceutical …, 2012 - Elsevier
… The objective of the study was to develop chitosan (CH) coated sodium alginate–chitosan (…
was to develop chitosan coated sodium alginate nanoparticle of 5-FU for ocular delivery with …

Chitosan nanoparticles for meloxicam ocular delivery: development, in vitro characterization, and in vivo evaluation in a rabbit eye model

HB Mohamed, MA Attia Shafie, AI Mekkawy - Pharmaceutics, 2022 - mdpi.com
… Our results suggested that the provided chitosan nanoparticles as an ocular drug delivery
system can overcome the irritant side effect of MLX chronic use. Therefore, the selected MLX-…

The potential application of hyaluronic acid coated chitosan nanoparticles in ocular delivery of dexamethasone

MA Kalam - International journal of biological macromolecules, 2016 - Elsevier
… of DEX in to eyes, we developed chitosan (CS) based nanoparticles (NPs) and HA-coated
CS-… In this study the ocular irritation potential of chitosan nanoparticles was performed, in vitro …

Preparation and evaluation of N-trimethyl chitosan nanoparticles of flurbiprofen for ocular delivery

UA Shinde, PN Joshi, DD Jain, K Singh - Current eye research, 2019 - Taylor & Francis
… N-trimethyl chitosan (TMC), a water-soluble chitosan derivative and to prepare … nanoparticles
for treatment of bacterial conjunctivitis which aims to increase the residence time in ocular

Preparation and evaluation of naringenin-loaded sulfobutylether-β-cyclodextrin/chitosan nanoparticles for ocular drug delivery

P Zhang, X Liu, W Hu, Y Bai, L Zhang - Carbohydrate polymers, 2016 - Elsevier
The aim of this study was to prepare and characterize the naringenin-loaded sulfobutylether-β-cyclodextrin/chitosan
nanoparticles (Nag-CD/CS-NPs) and evaluate their potential for the …

Chitosan nanoparticles of 5-fluorouracil for ophthalmic delivery: characterization, in-vitro and in-vivo study

RC Nagarwal, PN Singh, S Kant, P Maiti… - Chemical and …, 2011 - jstage.jst.go.jp
… Polymeric nanoparticulate systems have been evaluated as ocular drug delivery to enhance
the absorption of therapeutic drugs to improve bioavailability, reduce side effects, and sus…

Chitosan nanoparticles: a contribution to nanomedicine

H Peniche, C Peniche - Polymer International, 2011 - Wiley Online Library
… In particular, chitosan nanoparticles have become … Chitosan nanoparticles have been found
appropriate for non-invasive routes of drug administration: oral, nasal, pulmonary and ocular

Amphotericin-B entrapped lecithin/chitosan nanoparticles for prolonged ocular application

YS Chhonker, YD Prasad, H Chandasana… - International journal of …, 2015 - Elsevier
… in ophthalmic drug delivery is limited by the low precorneal residence at ocular surface as a
… /chitosan nanoparticles for prolonged ocular application. The prepared nanoparticles were …