A review of the preparation, characterization, and applications of chitosan nanoparticles in nanomedicine

R Jha, RA Mayanovic - Nanomaterials, 2023 - mdpi.com
… synthesis methods used to produce chitosan nanoparticles and nanostructures, such as ionic
… , we review drug delivery applications of chitosan nanoparticles, including for ocular, oral, …

Chitosan-coated PLGA nanoparticles of bevacizumab as novel drug delivery to target retina: optimization, characterization, and in vitro toxicity evaluation

J Pandit, Y Sultana, M Aqil - Artificial cells, nanomedicine, and …, 2017 - Taylor & Francis
… and optimize the chitosan (CS)-coated poly(lactide-co-glycolic acid) (PLGA) nanoparticles
(NPs) of bevacizumab for sustained and effective delivery to posterior ocular tissues. NPs …

Microscopic and spectroscopic evaluation of novel PLGA–chitosan Nanoplexes as an ocular delivery system

GK Jain, SA Pathan, S Akhter, N Jayabalan… - Colloids and Surfaces B …, 2011 - Elsevier
Chitosan nanoparticles and nanocapsules have shown interesting properties and … carriers
across the ocular mucosa. Although chitosan nanoparticles reside on the ocular surface for a …

Preparation and characteristics of a thermosensitive in situ gel loaded with chitosan nanoparticles for optimal ocular delivery of chloramphenicol

C Huang, L Peng, X Xu, Y Lu, X Wang, Z Lan… - Journal of Drug Delivery …, 2023 - Elsevier
… ) and extend ocular retention, chitosan nanoparticles carrying … , antimicrobial activity, and
ocular irritancy. The average … study provides a valuable carrier for effective CAP delivery. …

Chitosan Nanoparticles as Vehicle for Prolonged Ocular Delivery of Ofloxacin

B Rao Bandaru, K Senthilkumar… - Pharmaceutical …, 2014 - ingentaconnect.com
… are the proven promising drug delivery vehicle in ocular applications … chitosan nanoparticle
as a new vehicle for the improvement of the delivery of the antibiotic ofloxacin to the ocular

Preparation and characterization of novel drug-inserted-montmorillonite chitosan carriers for ocular drug delivery

D Hou, R Gui, S Hu, Y Huang… - … in nanoparticles, 2015 - geographical.go2journals.com
chitosan nanoparticles has shown the interaction and prolonged residence time of chitosan
nanoparticles at the ocular … also been investigated for the treatment of ocular infections [14]…

Topical Application of Linezolid–Loaded Chitosan Nanoparticles for the Treatment of Eye Infections

M Alkholief, MA Kalam, AK Alshememry, R Ali… - Nanomaterials, 2023 - mdpi.com
… Thus, we develop non–invasive nanocarriers (CSNPs) for topical ocular delivery of LZ to
treat the increasing multi–drug–resistant eye infections. The CSNPs prolong the …

Development of Dorzolamide Loaded 6-O‐Carboxymethyl Chitosan Nanoparticles for Open Angle Glaucoma

U Shinde, MH Ahmed, K Singh - Journal of drug delivery, 2013 - Wiley Online Library
… Modified ocular drug delivery systems like ocular inserts and in-situ gelling systems, though
… that polymeric nanoparticles could serve as a best suited option in topical ocular delivery. …

Chitosan-based nanoparticles for ocular drug delivery

K Pal, BK Pradhan, D Kim, M Jarzębski - Advances in biomedical polymers …, 2023 - Elsevier
… residence of the chitosan nanoparticles was enhanced when converted into an in situ gel
formulation. Further, the chitosan nanoparticles did not induce irritation of the ocular tissue. …

Chitosan derivatives as effective nanocarriers for ocular release of timolol drug

PI Siafaka, A Titopoulou, EN Koukaras… - International journal of …, 2015 - Elsevier
… The dissolution mechanism of chitosan nanoparticles is characterized by a triphasic pattern.
An initial burst release was recorded that followed by a slower release, during which the …