… , chloroquine and hydroxychloroquine … hydroxychloroquine is the cornerstone in the treatment
of several auto-immune disorders. There is convincing evidence that hydroxychloroquine …

… Critical appraisal of the evidence was done by Cochrane risk of bias tool and Newcastle
Ottawa Scale. The quality of evidence was graded as per the GRADE approach. …

… Table 1 enumerates the findings of the in vitro pre-clinical studies and Table 2 denotes
the critical appraisal of the clinical opinions. The pre-clinical studies showed the prophylactic …

… chloroquine and hydroxychloroquine (… chloroquine to inhibit the replication of SARS-CoV-2
in Vero E6 cells culture by approximately 80% (7). HCQ, a less toxic derivative of chloroquine…

… Chloroquine and hydroxychloroquine were among the first drugs considered for treatment
of coronavirus disease 2019 (COVID-19) (1). Both have demonstrated in vitro antiviral efficacy …

… As implication for practice, this review did not find sufficient evidence to support the use of
hydroxychloroquine or chloroquine as a routine for treating all patients with COVID-19, neither …

… Of particular interest are chloroquine (CQ) and hydroxychloroquine (HCQ). The aims of this
systematic review are to systematically identify and collate 24 studies describing the use of …

BACKGROUND & AIMS Hydroxychloroquine (HCQ) and chloroquine (CQ) are anti-malarial
drugs frequently used in the rheumatologic field. They were recently identified as potential …

… Increasing number of clinical trials from the onset of the COVID-19 pandemic has revealed
that hydroxychloroquine and chloroquine are not only profitable but also deleterious. …

Objectives We critically evaluated the quality of evidence and quality of harm reporting in
clinical trials that evaluated the effectiveness of hydroxychloroquine (HCQ) or chloroquine (CQ) …