Hydroxychloroquine and chloroquine for treatment of SARS-CoV-2 (COVID-19)

KA Pastick, EC Okafor, F Wang… - Open forum …, 2020 - academic.oup.com
… of hydroxychloroquine/chloroquine against SARS-CoV-2 has yet to be fully elucidated.
Chloroquine was first studied in SARS-CoV [30], … for the 2002–2003 SARS coronavirus epidemic. …

Hydroxychloroquine, a less toxic derivative of chloroquine, is effective in inhibiting SARS-CoV-2 infection in vitro

J Liu, R Cao, M Xu, X Wang, H Zhang, H Hu, Y Li, Z Hu… - Cell discovery, 2020 - nature.com
… ) and chloroquine (CQ) phosphate, efficiently inhibited SARS-CoV-… of the first patient infected
by SARS-CoV-2 in the United States 2 , … of chloroquine and hydroxychloroquine. Scand. J. …

Safety considerations with chloroquine, hydroxychloroquine and azithromycin in the management of SARS-CoV-2 infection

DN Juurlink - Cmaj, 2020 - Can Med Assoc
… the use of chloroquine and hydroxychloroquine for treatment … hydroxychloroquine prophylaxis
for health care workers.12 … with use of chloroquine and hydroxychloroquine — and to a …

Chloroquine and hydroxychloroquine in covid-19

RE Ferner, JK Aronson - Bmj, 2020 - bmj.com
… of chloroquine or hydroxychloroquine. For now, except for supportive measures, infection with
SARS-CoV-2 … . Chloroquine is a potent inhibitor of SARS coronavirus infection and spread. …

[PDF][PDF] Efficacy of chloroquine and hydroxychloroquine in the treatment of COVID-19.

SA Meo, DC Klonoff, J Akram - European Review for …, 2020 - talkingaboutthescience.com
… Chloroquine is a potent inhibitor of SARS coronavirus infection and spread. Virol J 2005;
2: 69. 13) Wang M, Cao r, zHang l, Yang X, liU j, XU M, SHi z, HU z, zHong W, Xiao g. …

Structural and molecular modelling studies reveal a new mechanism of action of chloroquine and hydroxychloroquine against SARS-CoV-2 infection

J Fantini, C Di Scala, H Chahinian, N Yahi - International journal of …, 2020 - Elsevier
… The recent emergence of the novel pathogenic SARS-coronavirus 2 (SARS-CoV-2) is …
showed that chloroquine (CLQ), one of the drugs currently under investigation for SARS-CoV-2 …

[HTML][HTML] Insights into antiviral mechanisms of remdesivir, lopinavir/ritonavir and chloroquine/hydroxychloroquine affecting the new SARS-CoV-2

K Uzunova, E Filipova, V Pavlova, T Vekov - Biomedicine & …, 2020 - Elsevier
CoV-infected cells. Numerous studies demonstrated the ability of remdesivir to inhibit
SARS-CoV… of lopinavir/ritonavir and chloroquine/hydroxychloroquine in SARS-CoV-2 infected …

[PDF][PDF] Chloroquine and hydroxychloroquine as available weapons to fight COVID-19

P Colson, JM Rolain, JC Lagier, P Brouqui… - International journal of …, 2020 - Elsevier
… on viruses is probably the same as that of chloroquine, since the 69 mechanism of action …
hydroxychloroquine, which would be therefore our first choice in the treatment of 71 SARS-CoV-…

Effect of chloroquine, hydroxychloroquine, and azithromycin on the corrected QT interval in patients with SARS-CoV-2 infection

M Saleh, J Gabriels, D Chang, B Soo Kim… - Circulation …, 2020 - Am Heart Assoc
… glycosylation of cellular receptors of SARS-CoV. Compared with chloroquine, hydroxychloroquine
has been shown in vitro to have higher inhibition against SARS-CoV-2. These limited …

Chloroquine and hydroxychloroquine for the treatment of COVID-19: a systematic review and meta-analysis

A Elavarasi, M Prasad, T Seth, RK Sahoo… - Journal of general …, 2020 - Springer
… 2 (SARS-CoV-2) is responsible for the coronavirus disease … Among such drugs,
hydroxychloroquine (HCQ) was one of the … efficacy of chloroquine (CQ) and HCQ for the …