Cholesterol metabolism in neurodegenerative diseases: molecular mechanisms and therapeutic targets

L Dai, L Zou, L Meng, G Qiang, M Yan, Z Zhang - Molecular neurobiology, 2021 - Springer
… However, the specific role of cholesterol metabolism disorder in the … cholesterol metabolism
and discussed the possible mechanisms of cholesterol metabolism and statin therapy

Cholesterol metabolism and therapeutic targets: rationale for targeting multiple metabolic pathways

SD Turley - Clinical Cardiology, 2004 - Wiley Online Library
… The liver also initially clears all the cholesterol that is absorbed from the small intestine. The
absorption of excess cholesterol can potentially increase the amount of cholesterol stored in …

Human cholesterol metabolism and therapeutic molecules

V Charlton‐Menys, PN Durrington - Experimental physiology, 2008 - Wiley Online Library
cholesterol biosynthesis and transfer and the development of drugs for the regulation of
cholesterol metabolism… the realization that circulating LDL cholesterol could be decreased when …

[HTML][HTML] Regulation of cholesterol homeostasis in health and diseases: from mechanisms to targeted therapeutics

Y Duan, K Gong, S Xu, F Zhang, X Meng… - … and Targeted Therapy, 2022 - nature.com
… or enhancing cholesterol utilization … cholesterol homeostasis, and the cholesterol-lowering
interventions in clinics or in preclinical studies as well as new cholesterol-lowering targets

Cholesterol metabolism: a potential therapeutic target in Mycobacteria

A Abuhammad - British journal of pharmacology, 2017 - Wiley Online Library
… progress in targeting cholesterol metabolism as a novel strategy for generating effective and
safe short-term antitubercular drugs that would provide new therapeutic options for TB, MDR…

SREBPs: regulators of cholesterol/lipids as therapeutic targets in metabolic disorders, cancers and viral diseases

AK Walker, AM Näär - Clinical Lipidology and Metabolic …, 2012 - search.proquest.com
… ) may also serve as novel therapeutic targets to ameliorate cardiometabolic diseases. Taken
targets of therapies to limit lipid/cholesterol synthesis or membrane production in metabolic

Cholesterol metabolism as a potential therapeutic target and a prognostic biomarker for cancer immunotherapy

H Zhang, W Zhao, X Li, Y He - OncoTargets and therapy, 2021 - Taylor & Francis
… preclinical and clinical studies on cholesterol metabolism in immunotherapy, this review
aimed to explore the potential effects of cholesterol metabolism on immunotherapy. We present …

[HTML][HTML] Cholesterol metabolism: A potential therapeutic target in glioblastoma

F Ahmad, Q Sun, D Patel, JM Stommel - Cancers, 2019 - mdpi.com
… amino acid metabolism in GBM, in this review we will discuss the role of cholesterol
metabolism in influencing tumor cell growth and proliferation and as a potential therapeutic target. …

Cholesterol metabolism: new functions and therapeutic approaches in cancer

H Xu, S Zhou, Q Tang, H Xia, F Bi - … et Biophysica Acta (BBA)-Reviews on …, 2020 - Elsevier
cholesterol metabolism. Understanding the regulation mechanisms of SOAT1 expression in
cancer and exploring new therapeutic targets are of great significance to clinical application. …

Cholesterol metabolism is a potential therapeutic target in Duchenne muscular dystrophy

F Amor, A Vu Hong, G Corre, M Sanson… - Journal of cachexia …, 2021 - Wiley Online Library
cholesterol-independent. Our results support that HMGCR and the accumulation of cholesterol
in the muscle are the direct therapeutic targets … of cholesterol metabolism abnormalities in …