… Kidney disease in perspective – inadequacy of current treatments Chronic kidney disease
(CKD) is defined as a disease with gradual and persistent loss of renal function over an …

… After the initial phase of injury, early inflammation is followed by the infiltration of circulating
immune cells (T- and B-cells) attracted by cytokines and damage-associated molecular …

… Necroptosis is a process that starts with the release of damage-associated molecular
patterns (DAMPs) and is controlled through phosphorylation of RIPK1, RIPK2, RIPK3 (representing …

… CKD (chronic kidney disease) is a severe and complex disease with a very high prevalence
… CKD patients are exposed to haemodynamic disturbances in addition to severe metabolic …

… In the present study, a gene VNN1 among the CKD-related molecules was also found to be
up-regulated in CKD, (8.23 fold increase to control without statistical significance [P > 0.05]). …

… molecules, facilitated by leukocyte adhesion molecules. Functionally heterogeneous
macrophages secrete many fibrosis-promoting molecules… synthesize the molecules that activate …

… SDMA-enriched HDL acts as a damage-associated molecular pattern and activates Toll-like
receptor 2 (TLR2), which links abnormal HDL to innate immunity activation, endothelial …

… to kidney failure, complications of lessening kidney function, and … into the molecular mechanism
of chronic kidney disease. We … -associated lipocalin, matrix metalloproteinases, the gut–…

… in the interaction amongst these molecules could alter kidney function, thus rendering …
damage-associated molecular patterns (DAMPs) and pathogen-associated molecular patterns (…

… , presence and degree of proteinuria and in patients with ESRD, modality of renal … the
molecular mechanisms which cause dyslipidemia and the nature of lipid disorders associated with …