Cellular mechanisms of human atherogenesis: focus on chronification of inflammation and mitochondrial mutations

AM Markin, IA Sobenin, AV Grechko, D Zhang… - Frontiers in …, 2020 - frontiersin.org
Atherosclerosis is one of the most common diseases of the cardiovascular system that leads
to the development of life-threatening conditions, such as heart attack and stroke. …

Cellular Mechanisms of Human Atherogenesis: Focus on Chronification of Inflammation and Mitochondrial Mutations

D Zhang - … in Medical Biochemistry, Genomics, Physiology, and …, 2021 - books.google.com
Atherosclerosis is a multifactorial disease with a complex pathogenesis. Multiple factors were
shown to be involved in atherosclerotic lesion formation, and many knowledge gaps still …

Possible role of mitochondrial DNA mutations in chronification of inflammation: focus on atherosclerosis

AN Orekhov, NN Nikiforov, EA Ivanova… - Journal of clinical …, 2020 - mdpi.com
… In this review, we discuss cellular mechanisms of atherosclerosis development. During
the last decade, studies of atherosclerosis pathogenesis have been conducted mostly on …

Chronification of pain: mechanisms, current understanding, and clinical implications

DJ Pak, RJ Yong, AD Kaye, RD Urman - Current pain and headache …, 2018 - Springer
… Surgery-associated tissue injury can lead to persistent inflammatory states that facilitate
peripheral and central sensitization. Chronic post-surgical pain (CPSP), defined as pain that …

The role of mitochondrial mutations in chronification of inflammation: hypothesis and overview of own data

AN Orekhov, NG Nikiforov, AV Omelchenko, VV Sinyov… - Life, 2022 - mdpi.com
Chronification of local inflammation in the arterial wall is, therefore, a crucial event in the …
Recent studies have improved our knowledge of cellular mechanisms of inflammatory response…

Somatic mutations of hematopoietic cells are an additional mechanism of body aging, conducive to comorbidity and increasing chronification of inflammation

YE Yegorov, AV Poznyak, EE Bezsonov, AD Zhuravlev… - Biomedicines, 2022 - mdpi.com
Inflammation and telomere-dependent cell senescence can … mechanism contributes to
the intensification of inflammatory processes in the body, we can assume that this mechanism

[HTML][HTML] Role of Mitochondria in the Chronification of Inflammation: Focus on Dysfunctional Mitophagy and Mitochondrial DNA Mutations

AN Orekhov, VI Summerhill, VA Khotina… - Gene …, 2023 - xiahepublishing.com
… In this respect, the mechanisms triggering defective … mitochondria to maintain cellular
homeostasis, attracted special … role and mechanisms of mitochondria in inflammation

Do mitochondrial DNA mutations play a key role in the chronification of sterile inflammation? Special focus on atherosclerosis

AN Orekhov, EV Gerasimova… - Current …, 2021 - ingentaconnect.com
… Chronic inflammation is the cause of 80% of morbidity and mortality as well as ageing; there…
the mechanisms of chronic inflammation is important and relevant. Cellular mechanisms of …

Molecular and cellular mechanisms of inflammation in atherosclerosis

NM Popa-Fotea, CE Ferdoschi… - Frontiers in …, 2023 - frontiersin.org
… the cell axis activation and specific mechanisms and pathways through which inflammation
cellular and molecular mechanisms of inflammation in atherosclerosis concentrating on key …

Tumor Necrosis Factor-Alpha and the Chronification of Acute Pain

DI Smith, H Tran - Pathogenesis of Neuropathic Pain: Diagnosis and …, 2022 - Springer
… interaction has helped indict another mechanism of TNF-α- mediated pain chronification. …
to play important roles in the inflammatory cell response cascade demonstrating modulating …