… colposcopy is appropriate if the cumulative risk of CIN 3+ over 2 years is at least 10%, offering
a risk-based referral to colposcopy … The threshold for referral for colposcopy set by Castle …

… referral for colposcopy but would encompass 10% of all CIN3+ … testing, referral to colposcopy
or biopsy based on risk. Five … high risk of CIN3+, colposcopic biopsy for substantial risk, …

… demonstrated that for Scenario 1, risk of colposcopy referral was initially higher in HPV1 …
to lower than the risk in BCS (Fig. 3). Initially the hazard of colposcopy referral was higher in …

… A high threshold for referral to colposcopy risks missing … Once the immediate risk of CIN3 is
ruled out by colposcopy … an initial colposcopy, we calculated that the 5-year risks of CIN3 for …

… risks, resulting in referral for colposcopy without HPV triage. However, new guidelines
recommending cotesting for women 30 years and older imply that clinicians will often receive the …

… to CIN III in seven women and downgraded from CIN III to CIN II in … abnormalities are associated
with a risk of CIN. fie would … , but with colposcopic referral if the abnormality is persistent. …

… on referral patterns into the colposcopy services and … -risk (CIN2/CIN3/adenocarcinoma
in-situ) histologies (p = 0.0058 × 10 −9 ). High-risk precancerous changes present a high risk of …

… We computed the absolute risk of developing CIN2 or more severe disease, and CIN3 or …
About half of colposcopy referrals in the UK are for women with borderline nuclear …

… Risk at the baseline screen is the risk of CIN 2+, CIN 3+, or cancer for Pap results or cotest
results where women are immediately referred for colposcopy … ASC-US, colposcopic referral is …