… We found that delivery of vector into the cisterna magna via … In addition, we evaluated the
inflammatory response to AAV9-… indicate that delivery of AAV9 into the cisterna magna is an …

… delivery. A safe and effective route to achieve global gene distribution in the CNS is needed,
and administration of genes through the cisterna magna (… a gene therapy delivery method to …

… scAAV9-GFP vector delivery via the cisterna magna revealed a significant … that cisterna
magna administration is a safe alternative to intracranial or intracerebroventricular vector delivery …

… PHP variants improve CNS targeting when delivered intrathecally in rats. We evaluated the
… ) of AAV.PHP.eB-CAG-GFP and AAV9-CAG-GFP when delivered into the cisterna magna of 6…

… of AAV serotype 9 (AAV9) vectors expressing GFP injected into the cisterna magna or lumbar
… We report that an intrathecal gene delivery of AAV9 in mice leads to stable transduction of …

… We consider intra-cisterna magna injection of AAV-GLUT1 to … Then, we injected AAV-GLUT1
into the cisterna magna of an … of AAV-GFP and AAV-GLUT1 in the CNS and other organs. …

… F]FB-AAV vectors were infused via the cisterna magna in two … subarachnoid space up to
the cisterna magna under X-ray … radioscopy, the [ 18 F]FB-AAV vector solution was slowly (for …

… Whole blood was collected from the rats via cardiac punctures and terminal CSF samples
were collected from the cisterna magna and both samples were then snap-frozen. …

… of AAV9 CSF injection. In both newborns and young cats, administration of AAV9-GFP in the
cisterna magna … tropism of AAV9 for MNs is not affected by age at CSF delivery. Surprisingly, …

… Intra-cisterna magna (ICM) delivery of AAV9 vectors shows high … delivery has not yet been
tested for the treatment of GAN. This study compared the efficacy of using ICM or LP delivery …