A review of SARS-CoV-2 and the ongoing clinical trials

YF Tu, CS Chien, AA Yarmishyn, YY Lin… - International journal of …, 2020 - mdpi.com
… of SARS-CoV-2 such as its epidemiological and clinical features, as well as its unique
contagious characteristics different from SARS-CoV and MERS-CoV, … against the SARS-CoV-2 …

The biological and clinical significance of emerging SARS-CoV-2 variants

K Tao, PL Tzou, J Nouhin, RK Gupta… - Nature Reviews …, 2021 - nature.com
… -2 evolution, the structure and function of the SARS-CoV-2 spike protein and the … , clinical
and public health communities to respond to the new threat posed by emerging SARS-CoV-2 …

Understanding neutralising antibodies against SARS-CoV-2 and their implications in clinical practice

NYL Pang, ASR Pang, VT Chow, DY Wang - Military Medical Research, 2021 - Springer
… in neutralising SARS-CoV-2, their persistence in convalescent individuals, and in reinfection.
Furthermore, we also review the applications of neutralising antibodies in the clinical setting…

Detection of SARS-CoV-2 in different types of clinical specimens

W Wang, Y Xu, R Gao, R Lu, K Han, G Wu, W Tan - Jama, 2020 - jamanetwork.com
… In this study, SARS-CoV-2 was detected in specimens from multiple sites of 205 patients
with COVID-19, with lower respiratory tract samples most often testing positive for the virus. …

Viral load of SARS-CoV-2 in clinical samples

Y Pan, D Zhang, P Yang, LLM Poon… - The Lancet infectious …, 2020 - thelancet.com
… diagnosis of SARS-CoV-2 infection.However, viral dynamics in infected patients are still yet
to be fully determined. Here, we report our findings from different types of clinical specimens …

The natural history, pathobiology, and clinical manifestations of SARS-CoV-2 infections

J Machhi, J Herskovitz, AM Senan, D Dutta… - Journal of neuroimmune …, 2020 - Springer
SARS-CoV-2, the cause of coronavirus 2019 (COVID-19) disease, belongs to the same …
coronavirus (SARS-CoV) and the Middle East respiratory syndrome coronavirus (MERS-CoV), …

Antibody responses to SARS-CoV-2 in COVID-19 patients: the perspective application of serological tests in clinical practice

Q Long, H Deng, J Chen, J Hu, B Liu, P Liao, Y Lin… - MedRxiv, 2020 - medrxiv.org
SARS-CoV-2 remains nearly unknown. In this study, we depicted the profiles of acute antibody
response against SARS-CoV-2 … We also demonstrated the clinical application of antibody …

SARS-CoV-2 pathophysiology and its clinical implications: An integrative overview of the pharmacotherapeutic management of COVID-19

A Tsatsakis, D Calina, L Falzone, D Petrakis… - Food and Chemical …, 2020 - Elsevier
… Moreover, SARS-CoV-2 can cause central and peripheral neurological manifestations, … of
contracting the SARS-CoV-2 virus. Considering the multitude of clinical symptoms of COVID-19…

Clinical phenotypes of SARS-CoV-2: implications for clinicians and researchers

J Rello, E Storti, M Belliato… - European Respiratory …, 2020 - Eur Respiratory Soc
… syndrome coronavirus 2 (SARS-CoV-… clinical experience from the SARS-CoV-2 surge
acquired from different hospitals in Italy and Spain (on 27 March 2020) and is supported by clinical

Development and clinical application of a rapid IgM‐IgG combined antibody test for SARSCoV‐2 infection diagnosis

Z Li, Y Yi, X Luo, N Xiong, Y Liu, S Li… - Journal of medical …, 2020 - Wiley Online Library
… M (IgM) and IgG antibodies simultaneously against SARSCoV‐2 virus in human blood within
… kit, we carried out clinical studies to validate its clinical efficacy uses. The clinical detection …