[HTML][HTML] Stratified randomization for clinical trials

WN Kernan, CM Viscoli, RW Makuch, LM Brass… - Journal of clinical …, 1999 - Elsevier
… She assumed that even without stratified randomization, the main analysis for treatment
effectiveness would be adjusted for convariates. Under a range of assumptions about treatment …

Clinical benefit of steroid use in patients undergoing cardiopulmonary bypass: a meta-analysis of randomized trials

RP Whitlock, S Chan, PJ Devereaux, J Sun… - European heart …, 2008 - academic.oup.com
… meta-analysis of randomized trials reporting the effects of prophylactic steroids on clinical
outcomes … We included 44 trials randomizing 3205 patients. Steroids reduced new onset atrial …

[HTML][HTML] Randomization in clinical studies

CY Lim, J In - Korean journal of anesthesiology, 2019 - synapse.koreamed.org
analysis may show the problem of poor power. To avoid this, we set blocks for randomization
… When using blocks, we need to apply multiple blocks and randomize within each block. At …

[图书][B] Randomization in clinical trials: theory and practice

WF Rosenberger, JM Lachin - 2015 - books.google.com
… the particular randomization design into analyses. Currently, I … , and statistical issues for
randomized clinical trials can be very … shall address randomization in the context of clinical trials. …

Benefit of early invasive therapy in acute coronary syndromes: a meta-analysis of contemporary randomized clinical trials

AA Bavry, DJ Kumbhani, AN Rassi, DL Bhatt… - Journal of the American …, 2006 - jacc.org
… Our analysis of 7 contemporary randomized trials in over 8,000 NSTE-ACS patients treated
… Although later angiography in our analysis was associated with improved survival, we would …

An overview of randomization techniques: An unbiased assessment of outcome in clinical research

KP Suresh - Journal of human reproductive sciences, 2011 - journals.lww.com
… Statistical techniques such as analysis of covariance (… imbalance in the analysis stage of the
clinical research. However, … sound randomization in the design stage of a clinical research (…

A roadmap to using randomization in clinical trials

…, Randomization Innovative Design Scientific … - BMC medical research …, 2021 - Springer
… investigators and biostatisticians who are tasked with the design, conduct, analysis, and
interpretation of clinical trial results, as well as regulatory and scientific/medical journal reviewers…

Randomization: The forgotten component of the randomized clinical trial

WF Rosenberger, D Uschner, Y Wang - Statistics in medicine, 2019 - Wiley Online Library
… , that must form part of our design, provides the justification for a randomization analysis
of our observed result. We need only choose a measure of extremeness of result, and learn …

Clinical benefit of statin pretreatment in patients undergoing percutaneous coronary intervention: a collaborative patient-level meta-analysis of 13 randomized studies

G Patti, CP Cannon, SA Murphy, S Mega, V Pasceri… - Circulation, 2011 - Am Heart Assoc
… and the clinical benefit of high-dose statins observed in the present meta-analysis may
be affected; a standardized approach to antithrombotic therapies in a larger randomized trial …

Stopping randomized trials early for benefit and estimation of treatment effects: systematic review and meta-regression analysis

D Bassler, M Briel, VM Montori, M Lane, P Glasziou… - Jama, 2010 - jamanetwork.com
Context Theory and simulation suggest that randomized controlled trials (RCTs) stopped early
for benefit (truncated RCTs) systematically overestimate treatment effects for the outcome …