… Various classification and diagnostic CSS criteria exist and include clinical, laboratory,
pathologic, and genetic features. Familial HLH results from cytolytic homozygous genetic defects …

… A hyperinflammatory state resulting in a cytokine storm and adult … of COVID-19 associated
cytokine storm (COVID-CS). … , and there are a few small ongoing clinical trials, including …

… In this review, we have critically compared the clinical impact of several potential therapeutic
agents that could block or interfere with the cytokine storm, such as IL-1 inhibitors, IL-6 …

… significance of cytokines. [ 3 ] The early recognition of cytokine storm by monitoring cytokine
levels … Definitely, an overall consideration on the assay performance, clinic needs, and POC …

… cytokine storm in some critical illness patients. Here, we summarize the pathogenesis, clinical
… Here, we propose a basic principle for consideration of CSS in COVID-19: (i) a sudden or …

… This comprehensive review helps to interpret the clinical results of the several trials ongoing…
IL-6 is a central player in the cytokine storm acting as a tissue injury enhancer, through the …

… , is the pioneer of the hyperinflammatory condition and cytokine storm in severe COVID-19. …
, ongoing clinical trials and special clinical considerations of using different IL-6 inhibitors …

… cytokines and is closely associated with poor prognosis. These excessively secreted pro-inflammatory
cytokines … Therefore, it is clinically important to understand the initiation and …

… and clinical studies, addressing the issue of which chemokines are more deeply involved
in the pathogenesis of the cytokine storm, potentially driving a more or less severe clinical …

… -19 pathophysiology or of cytokine storm, but rather to … clinically-relevant dynamic approach
to cytokine storm is proposed for treatment and follow-up in affected patients. Consideration …