[HTML][HTML] The cytokine storm in COVID-19: the strongest link to morbidity and mortality in the current epidemic

M Basheer, E Saad, N Assy - COVID, 2022 - mdpi.com
… The purpose of this review is to emphasize the importance of the cytokine storm situation …
The cytokine storm plays an essential role in the pathogenesis and clinical outcome of virus …

… with cytokine-storm targeting antibodies and challenges associated with development of novel monoclonal antibodies for the treatment of COVID-19 clinical cases

AM Johnson, R Barigye… - Human Vaccines & …, 2021 - Taylor & Francis
… monoclonal antibodies (mAbs) targeting cytokines that cause adverse COVID-… cytokine
storm (CS)-associated pathological complexities in some COVID-19 patients may limit the clinical

[PDF][PDF] Determining the disease outcome by cytokine storm during infectious diseases and targeting cytokines during sepsis: possible therapeutic options.

T Amin, A Hossain, FB Zahed - Journal of Advanced …, 2022 - researchgate.net
… in COVID-19—immunopathological mechanisms, clinical considerations, and therapeutic
approaches: the reprogram consortium position paper. Frontiers in Immunology, (2020).11. [83…

Criteria for cytokine storm syndromes

F Minoia, S Davì, A Alongi, A Ravelli - Cytokine Storm Syndrome, 2019 - Springer
… [14, 17], which were retained for further consideration even if they did not meet all statistical
… the cytokine blockers canakinumab and tocilizumab in randomized controlled clinical trials …

[HTML][HTML] Anakinra in COVID-19: important considerations for clinical trials

A King, A Vail, C O'Leary, C Hannan… - The Lancet …, 2020 - thelancet.com
Cytokine storm complicating macrophage activation syndrome associated with rheumatic
disease shares considerable biochemical overlap with the hyperinflammation observed in …

Lung under attack by COVID-19-induced cytokine storm: pathogenic mechanisms and therapeutic implications

C Pelaia, C Tinello, A Vatrella… - Therapeutic …, 2020 - journals.sagepub.com
… for the widespread clinical syndrome known … considerations, the present review will focus
on the pathogenic mechanisms underpinning the lung damage induced by the cytokine storm

[HTML][HTML] Cytokine storm syndrome in SARS-CoV-2 infections: a functional role of mast cells

B Hafezi, L Chan, JP Knapp, N Karimi, K Alizadeh… - Cells, 2021 - mdpi.com
… into consideration for cytokine release syndrome [83] and retrospective studies in COVID-19
patients demonstrated that tocilizumab might be clinically beneficial [65,66]. Clinical trials …

Cytokine storm in the pathophysiology of COVID-19: Possible functional disturbances of miRNAs

M Aslani, SS Mortazavi-Jahromi, A Mirshafiey - International …, 2021 - Elsevier
… This virus induces an intense cytokine response called cytokine storm in a group of patients
with severe/critical form. This event, in turn, results in serious clinical outcomes such as …

Targeting inflammatory cytokine storm to fight against COVID-19 associated severe complications

R Hirawat, MA Saifi, C Godugu - Life sciences, 2021 - Elsevier
… However, the activation of cytokine storm as a result of hyperactive immune response leads
… in vitro as well as clinical studies have shown a definite role of cytokine storm in SARS-CoV-2…

Cytokine storm: When the immune system goes into overdrive

PP Kale, A Mani, S Gurha, HN Abhishek… - Journal of Cellular …, 2023 - content.iospress.com
cytokines involved, such as IL-6 storm or TNF-alpha storm. Each type of cytokine storm
can have unique clinical features and treatment considerations, and early recognition and …